Hemorrhoids Clinical Trial
Official title:
A Randomised Controlled Trial Comparing Conventional Open Haemorrhoidectomy and Laser Haemorrhoidoplasty in the Treatment of Symptomatic Haemorrhoids: COHLAH Trial
Haemorrhoids or piles are the most common colorectal condition in the local population. Patients often present with bleeding with bowel movement or anal discomfort, both of which causes significant anxiety and stress. For symptomatic sizeable piles, the treatment of choice still remains the conventional open excision (COH). However, this technique carries with it a significant risk of bleeding and pain immediately after the operation, leading to some period of discomfort for the patients. The laser haemorrhoidoplasty procedure (LAH) has been shown in preliminary studies to have less pain, and less complications compared to COH. This study aims to directly compare these two techniques in a local Asian population. The investigators would be conducting a single-centre RCT simultaneously comparing the conventional open Milligan-Morgan haemorrhoidectomy (COH) and the laser haemorrhoidoplasty procedure (LAH) for the treatment of symptomatic grade ll-lV haemorrhoids. Primary outcomes will be post-operative pain while secondary outcomes include post-operative bleeding, readmission and/or reoperations, haemorrhoid-related quality of life (QoL) results and recurrence of symptoms up to a year post procedure
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT06216223 -
Laser Versus Surgery in Anal Diseases in Inflammatory Bowel Patients
|
N/A | |
| Withdrawn |
NCT02851940 -
Pain and Bleeding Following Hypertonic Saline Sclerotherapy Compared to Brand Ligation for Symptomatic Hemorrhoids
|
N/A | |
| Recruiting |
NCT02301052 -
Evaluation of Allium Ampeloprasum Spp.Iranicum Cream Effect for the Management of Hemorrhoids Symptoms
|
Phase 1/Phase 2 | |
| Completed |
NCT02216305 -
HAL-RAR Versus Hemorrhoidectomy in the Treatment of Grade III-IV Hemorrhoids. Prospective, Randomized Trial
|
N/A | |
| Completed |
NCT02358174 -
Hemorrhoids and Metalloproteinases, Observational Study
|
N/A | |
| Completed |
NCT01483833 -
Efficacy Study of Iferanserin to Treat Hemorrhoids
|
Phase 2 | |
| Completed |
NCT00397137 -
Stapled Anopexy Versus Closed Haemorrhoidectomy for Haemorrhoids
|
N/A | |
| Completed |
NCT00841620 -
Symptom Control 1-year After Circular Stapler Anopexy or Diathermy Excision for Prolapsed Haemorhoids
|
Phase 4 | |
| Completed |
NCT06459739 -
Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery
|
N/A | |
| Completed |
NCT04276298 -
Topical Analgesia Post-Haemorrhoidectomy
|
Phase 2/Phase 3 | |
| Completed |
NCT04675177 -
Polidocanol Foam VS Artery Ligation in Hemorrhoidal Disease
|
Phase 2/Phase 3 | |
| Recruiting |
NCT05889962 -
Ultrasound-guided Pudendal Nerve Block for Pain After Hemorrhoidectomy
|
N/A | |
| Recruiting |
NCT01961739 -
Topical 2% Lidocaine for the Treatment of Symptomatic Hemorrhoids
|
Phase 2/Phase 3 | |
| Active, not recruiting |
NCT02061176 -
THD Versus Open Haemorrhoidectomy
|
N/A | |
| Withdrawn |
NCT00512044 -
Local Versus General Anaesthesia in Stapled Hemorrhoidectomy
|
Phase 4 | |
| Completed |
NCT04031131 -
The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids
|
Phase 2 | |
| Completed |
NCT04567485 -
Impact of Moderate to Severe Pain in the Post-intervention Monitoring Room After Hemorrhoidectomy on the Length of Stay in the Outpatient Surgery Unit
|
||
| Completed |
NCT05247333 -
Implementation of a Minor Ailment Service in Community Pharmacy Practice
|
N/A | |
| Completed |
NCT03298997 -
Ligation and Hemorrhoidopexy Technique Versus Ligation of Hemorrhoidal Arteries Using Ultrasound for Hemorrhoids
|
N/A | |
| Completed |
NCT05605080 -
Hemostatic and Analgesic Effect of Gel Foam and Gauze With Bosmin After Anal Surgery
|
N/A |