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Hemorrhage clinical trials

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NCT ID: NCT04491669 Not yet recruiting - CKD Clinical Trials

Screening of Gastrointestinal Tract Bleeding Causes Among Chronic Renal Failure Patients

Start date: October 1, 2020
Phase:
Study type: Observational

The aim of the current study is to screen different causes and characteristics of Gastrointestinal bleeding in Chronic Renal Failure patients at Assuit University Hospital according to their stages based on e GFR (Stage I to IV), in order to assess different modalities of therapeutic intervention from medical therapy up to therapeutic intervention.

NCT ID: NCT04446533 Not yet recruiting - Periodontitis Clinical Trials

Effect of a Hydrogen-Peroxide and Hyaluronic-Acid Mouthwash (BMG0703) in the Treatment of Periodontitis

Start date: June 2020
Phase: Phase 3
Study type: Interventional

Assessment of the efficacy of BMG0703 in the treatment of periodontitis and control of supragingival plaque, compared to Chlorhexidine and a placebo product

NCT ID: NCT04438421 Not yet recruiting - Gingivitis Clinical Trials

Efficacy of Hyaluronic-acid and Hydrogen-Peroxide Mouthwash in Gingivitis Treatment

Start date: June 2020
Phase: Phase 3
Study type: Interventional

A clinical study to evaluate the efficacy and safety of a mouthwash containing Hydrogen Peroxide, Sodium Hyaluronate and Glycine in the prevention and management of complications associated gingivitis by film forming action.

NCT ID: NCT04436575 Not yet recruiting - Clinical trials for Acute Gastrointestinal Bleeding

Point-of-care Ultrasound Interest in Acute Gastrointestinal Bleeding Emergency Department Patients

Start date: July 1, 2020
Phase:
Study type: Observational

Acute Gastrointestinal (GI) Bleeding are a common chief complaint among Emergency Department. The mortality rate for Lower GI Bleeding is 3.9%. While the mortality rate can be as high as 10% for Upper GI Bleeding. Most existing scores take into account hemodynamic parameters such as systolic blood pressure or heart rate. Studies have shown that hemodynamic instability only develops late in the course of a bleed, as evidenced by a blood depletion of 30 to 40% of the total blood volume. Currently, few studies have examined the value of echocardiography in the management of patients presenting for Acute GI Bleeding in the Emergency Department. The main objective of this study is to show whether simple ultrasound parameters can, combined with clinico biological parameters, predict in an early manner the evolution of the patient presenting to the Emergency Department for Acute Gastrointestinal Bleeding.

NCT ID: NCT04406116 Not yet recruiting - Clinical trials for Actual or Potential Nonvariceal Bleeding in the Upper Gastrointestinal (GI) Tract

Clinical Evaluation of the Safety and Performance of Microwave Coagulation Using the HS1 Instrument

Start date: September 2020
Phase: N/A
Study type: Interventional

Clinical evaluation of the safety and performance of microwave coagulation using the HS1 Instrument for actual or potential non-variceal bleeding in the upper Gastrointestinal (GI) tract

NCT ID: NCT04400916 Not yet recruiting - Clinical trials for Subconjunctival Hemorrhage

Topical Tranexamic Acid After Intravitreal Injections

Start date: September 2020
Phase: N/A
Study type: Interventional

We aim to investigate whether topical administration of Tranexamic acid can reduce the occurence of subconjunctival hemorrahge after routine intravitreal injections for retinal conditions.

NCT ID: NCT04387305 Not yet recruiting - Hemorrhage Clinical Trials

Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study

TIC-TOC
Start date: October 1, 2024
Phase: Phase 3
Study type: Interventional

Trauma is the leading cause of death and disability in children in the United States. The objective of this study is to evaluate the benefits and harms of tranexamic acid (TXA; a drug that stops bleeding) in severely injured children with hemorrhagic brain and/or torso injuries. Using thromboelastography, we will measure baseline fibrinolysis to assess for treatment effects of TXA at different levels of fibrinolysis.

NCT ID: NCT04386642 Not yet recruiting - Meningioma Clinical Trials

Tranexamic Acid Reduce Blood Loss in Meningioma Resection

Start date: September 1, 2021
Phase: Phase 4
Study type: Interventional

In neurosurgical setting, a large sample size trials of tranexamic acid (TXA) has been limited to TBI and SAH. The evidence of TXA in brain tumor was scarce. A few case reports support the role of TXA in brain tumor patients with significant intraoperative bleeding and difficult achieving hemostasis. To prove the benefit of TXA for an attenuation of blood loss in brain tumor patients, research with a larger sample size is required. This prospective, randomized double-blind controlled study will be conducted to evaluate the effect of TXA in reducing blood loss and blood transfusion in patients with intracranial meningiomas, diameter > 5 cm in at least 2 dimensions from the latest radiographic findings.

NCT ID: NCT04346095 Not yet recruiting - Retinal Detachment Clinical Trials

Oral Sedation in Vitreoretinal Surgery

Start date: June 2020
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.

NCT ID: NCT04315623 Not yet recruiting - Bleeding Clinical Trials

RCA for CRRT in Hyperlactatemia Patient With Increased Bleeding Risk

Start date: March 30, 2020
Phase: N/A
Study type: Interventional

The purpose of this single center, randomized, control, open-labeled study is to evaluate the effect and safety of RCA versus no anticoagulation for CRRT in hyperlactatemia patients with increased bleeding risk.