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Hemorrhage, Surgical clinical trials

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NCT ID: NCT06038981 Completed - Bariatric Surgery Clinical Trials

Assessment of the Impact of Perioperative Administration of Tranexamic Acid on Bleeding After Sleeve Gastrectomy

Start date: July 4, 2022
Phase: N/A
Study type: Interventional

Enhanced recovery after bariatric surgery imposes a significant reduction in length of hospital stay. However beneficial for the overall recovery it reduces the hospital observation time. after a laparoscopic surgery during which one of the longest resection line in surgery or anastomosis are created. Therefore, discovering possible safe and effective ways of pharmacologically reducing surgical blood loss and reducing the risk of postoperative bleeding would be an invaluable addition to the protocol. The systemic use of tranexamic acid (TXA) has been shown to be effective in many types of surgery, reducing the incidence of post-operative bleeding and thereby reducing the rate of reoperation.

NCT ID: NCT05397652 Completed - Rotator Cuff Tears Clinical Trials

The Aim of This Study is to Examine the Effect of Intravenously Administered Tranexamic Acid (TXA) on the Visual Clarity, Perioperative Hemorrhage, Duration and Early Postoperative Course of Shoulder Arthroscopy in Beach Chair Position.

Start date: May 24, 2021
Phase: Phase 4
Study type: Interventional

Shoulder arthroscopy provides many benefits with a permanent increase in the possibilities and complexity of the application. A condition to perform it is intraoperative visual clarity dependent on hemorrhage control. The aim of this prospective, double blind, randomized, and controlled study is to examine the effect of intravenously administered tranexamic acid (TXA) on the visual clarity, perioperative hemorrhage, duration and early postoperative course of shoulder arthroscopy in beach chair position, which is not yet available in the literature. In the tested and control group, the investigators measure hemoglobin (Hb) in the waste irrigation fluid and the patient's blood before and after the procedure, visual clarity, duration of the procedure, postoperative shoulder swelling, pain level and analgesic drug consumption. The research uses scientific methods to determine if there is a reasonable basis for introducing TXA into routine clinical use.

NCT ID: NCT05385952 Completed - Liver Diseases Clinical Trials

GATT-Patch Versus TachoSil in Liver Surgery

Start date: August 4, 2022
Phase: N/A
Study type: Interventional

This is a pre-market, prospective, randomized (2:1), multicenter, multi-national pivotal clinical investigation. The purpose of this investigation is to determine the clinical safety and performance of GATT-Patch as compared with TachoSil for the management of minimal, mild, or moderate bleeding during elective open liver surgery.

NCT ID: NCT04976530 Completed - Clinical trials for Blood Loss, Surgical

Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)

STAR-T
Start date: August 31, 2021
Phase: N/A
Study type: Interventional

Prospective, multi-center, double-blind, randomized pivotal trial to evaluate the safety and effectiveness of the DrugSorb-ATR system for intraoperative removal of ticagrelor in patients undergoing urgent cardiothoracic (CT) surgery with cardiopulmonary bypass (CPB).

NCT ID: NCT04819945 Completed - Clinical trials for Hemorrhage, Surgical

Clinical Safety and Performance of GATT-Patch in Open Liver Surgery

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the clinical safety and performance of GATT-Patch for management of haemorrhage during elective open liver surgery.