KN057 Multiple Dose Study in Moderately Severe to Severe Hemophilia

Status Recruiting

Clinical Trial Summary

This study is designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of multiple subcutaneous doses of KN057 in subjects with hemophilia A or B, with or without inhibitors to Factor VIII (FVIII) or Factor IX (FIX). 24 adult participants 18 to 70 years of age with moderately severe to severe hemophilia A or hemophilia B (defined as FVIII or FIX activity ≤2%, respectively) with or without inhibitors (including 18 HA/HB patients without inhibitors and 6 HA/HB patients with inhibitors) are expected to be enrolled in this study during which they will receive prophylaxis treatment (defined as treatment by SC injection once weekly of KN057).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05421429
Study type	Interventional
Source	Suzhou Alphamab Co., Ltd.
Contact	Yanrong Dong, Master
Phone	+86 18914005458
Email	yanrongdong@alphamab.com
Status	Recruiting
Phase	Phase 2
Start date	July 7, 2022
Completion date	June 30, 2024

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