Hemophilia Clinical Trial
Official title:
Safety and Effectiveness of a Physiotherapy Intervention Through Movement Visualization in the Approach of Pain in Patients With Hemophilic Arthropathy. Multicenter Randomized Clinical Study.
Background. The recurrence of hemarthrosis in patients with hemophilia favors the development
of an intra-articular, degenerative and progressive lesion (hemophilic arthropathy). Pain is
one of the main clinical manifestations of this arthropathy.
Objective. Assess the safety and efficacy of an intervention in pain through visualization of
the movement using a mobile application of augmented reality and immersive 360º video,
regarding the frequency of bleeding and the improvement of pain perception and quality of
life, joint state , strength and functionality in patients with hemophilic arthropathy.
Study design. Randomized, multicenter, simple blind clinical study.
Method. 140 patients with hemophilia A and B will be recruited in this study. Patients will
be recruited in 5 regions of Spain. The 8 dependent variables will be: frequency of bleeding
(self-registration), pain (measured with the visual analogue scale and pressure algometer,
Tampa Scale of Kinesiophobia and Pain Catastrophizing Scale), quality of life (SF-12 scale),
anxiety (questionnaire Anxiety State-Trait-STAI), joint state (Hemophilia Joint Health Score
scale), muscular strength (dynamometer) and functionality (6-Minutes Walking test, Quick
Disabilities of the arm, shoulder and hand). Three evaluations will be carried out:
pre-treatment, post-treatment and after a 6-month follow-up period.
Expected results. Observe the effectiveness of movement visualization in the characteristics
of pain, and its implication in functionality, joint state, muscular strength and the
perception of quality of life in patients with hemophilic arthropathy.
n/a
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