Hemophilia A Clinical Trial
Official title:
Protected by Nature: Could Physical Activity Help to Counteract the Blood Haemophilia Disturbance? A Pilot Study.
Physical activity is lower in patients with haemophilia than in their healthy peers.
Nevertheless, exercize is recommended for those patients and supported by evidence. Until
2013, scientific and medical evidence to encourage physical activity for patients with
haemophilia were listed to increase their locomotor function, their metabolic status, their
fitness level and their well-being. In 2013, an original publication by Groen et al.
suggested that physical activity could also interact with the specific and biological
disturbance of the disease.
We propose to consider that regular endurance exercize prescription should be encouraged in
patients with haemophilia not only for a healthier lifestyle but also because it could
positively alter the specific biological blood disturbance seen in haemophilia.
Nevertheless, before planning a well powered intervention trial we need to determine the
acceptability of regular exercize and the expected value of factor Factor VIII, von
Willebrand factor and von Willebrand propeptide after an endurance training program.
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