Renal Dialysis Clinical Trial
Official title:
The LIPMAT Study: Liposomal Prednisolone to Improve Hemodialysis Fistula Maturation
This study will investigate if liposomal prednisolone is effective in promoting arteriovenous fistula (AVF) maturation when administered to human subjects after surgical creation of a radio-cephalic AVF.
AVFs are the preferred means of vascular access for maintenance hemodialysis. Nonmaturation occurs in 30-50% of cases, with highest rates in radio-cephalic fistulas. Inflammatory cytokines are involved in this process of nonmaturation. By suppressing inflammation, corticosteroids might promote maturation, but have significant systemic side effects. Liposomal prednisolone has a long circulation time and targets inflamed tissue with low systemic concentrations and limited side effects. In an animal study, it was demonstrated to promote AVF maturation. At present, no drug therapy aimed at improving shunt maturation is available. This study will investigate if liposomal prednisolone is effective in promoting AVF maturation when administered to human subjects after surgical creation of a radio-cephalic AVF. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05189795 -
The Construction of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients
|
||
| Completed |
NCT01125202 -
Intervention to Reduce Dietary Sodium in Hemodialysis
|
N/A | |
| Completed |
NCT00730145 -
A Single Dose Study Investigating The Elimination Of PD-0332334 In Patients Receiving Regular Hemodialysis
|
Phase 1 | |
| Completed |
NCT00806130 -
Health Related Quality of Life and Cognitive Function Among Norwegian Dialysis Patients
|
||
| Completed |
NCT00753116 -
Renal Denervation in End Stage Renal Disease Patients With Refractory Hypertension
|
Phase 1 | |
| Completed |
NCT05718765 -
The Effect of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients
|
N/A | |
| Completed |
NCT03250715 -
Effects of Low Level Laser Therapy on Functional Capacity and DNA Damage of Patients With Chronic Kidney Failure
|
N/A | |
| Completed |
NCT05469620 -
Adaptive Nutrition Therapy in Hemodialysis
|
N/A | |
| Completed |
NCT03536858 -
Social Networks and Renal Education: Promoting Transplantation
|
N/A | |
| Completed |
NCT00824837 -
Study of beta2-Microglobulin Removal by Standard Versus New High Cut-Off Haemodialysis Membrane
|
Phase 1/Phase 2 | |
| Completed |
NCT03403491 -
Study of Self-monitoring of Weight & Blood Pressure (Via patientMpower Platform) in Hemodialysis
|
N/A | |
| Completed |
NCT01179620 -
Certoparin in Renal Patients Undergoing Hemodialysis
|
Phase 3 | |
| Completed |
NCT01017276 -
A Phase 3 Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Peritoneal Dialysis
|
Phase 3 | |
| Active, not recruiting |
NCT04466865 -
A Communication Tool to Assist Older Adults Facing Dialysis Choices
|
N/A | |
| Recruiting |
NCT03782519 -
Quality of Life of Frail Aged Patients in Incremental Hemodialysis
|
N/A | |
| Recruiting |
NCT02843334 -
Study of the Prevalence of Fabry Disease in French Dialysis Patients
|
N/A | |
| Recruiting |
NCT02545530 -
Transdermal Clonidine in Chronic Hemodialysis Patients
|
N/A | |
| Completed |
NCT00892749 -
Long-term Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis
|
Phase 3 | |
| Completed |
NCT00649298 -
A Clinical Trial of IntensiVE Dialysis
|
Phase 4 | |
| Completed |
NCT05833451 -
Reiki in Symptom Management of Hemodialysis Patients
|
N/A |