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NCT05298761 Clinical Trial

Efficacy of I/v Nalbuphine v/s Iv Lignocain in Attanuation of Pressor Responseduring Laryngeoscopy and Intubation in Middle Age Patient Planned for Thyroid Surgery

Hemodynamic Stability Clinical Trial

Official title:
Efficacy of IV Lignocaine Versus IV Nalbuphine for Attenuation of Pressor Response Diring Laryngoscopy and Intubation in Patients Planned for Thyroid Surgery

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05298761
Other study ID # ASarwar
Secondary ID
Status Not yet recruiting
Phase Early Phase 1
First received
Last updated
Start date December 30, 2023
Est. completion date June 1, 2024

Study information
Verified date November 2023
Source Sheikh Zayed Medical College
Contact Dr.amna Sarwar, Fcps
Phone 03218337129
Email Dr.amnasabir@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Comparison of I/V nalbuphine versus I/V xylocain in attanuation of pressor response during intubation and laryngeoscopy in patients undergoing for thyroid surgery,selection of better supressor agent minimises the drug repated side effects like hypertention tachycardia but also helps in heamodynamically stability at induction.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 60
Est. completion date June 1, 2024
Est. primary completion date March 1, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria: - middle age(18_40) - Asa 1 and 2 - Non hypertensive - Thyroid patients - patient who gives consent Exclusion Criteria: - hypertensive - Asa 3 and 4 - Patient refusal

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Lignocaine
Inj lignocain and inj nalbuphine given to two groups of participants and effects of both drugs

Locations
Country Name City State
Pakistan Dr.amna Rahim Yar Khan Punjab

Sponsors (1)
Lead Sponsor Collaborator
Sheikh Zayed Medical College

Country where clinical trial is conducted

Pakistan, 

Outcome
Type Measure Description Time frame Safety issue
Primary Reduce stress response during intubation and hemodynamic stabilty Assesment of Hemodynamic stability by observing vital signs 10 minutes
Primary Achieve hemodynamic stabilty and smooth intubation Assesment of hemodynamic stability by clinical examination of vital signs 10 minutes
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