Clinical Trials Logo
  1. Home
  2. Hemodynamic Stability
  3. NCT05298761
  4. Details
NCT05298761 Clinical Trial

Efficacy of I/v Nalbuphine v/s Iv Lignocain in Attanuation of Pressor Responseduring Laryngeoscopy and Intubation in Middle Age Patient Planned for Thyroid Surgery

Hemodynamic Stability Clinical Trial

Official title:
Efficacy of IV Lignocaine Versus IV Nalbuphine for Attenuation of Pressor Response Diring Laryngoscopy and Intubation in Patients Planned for Thyroid Surgery

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05298761
Other study ID # ASarwar
Secondary ID
Status Not yet recruiting
Phase Early Phase 1
First received
Last updated
Start date December 30, 2023
Est. completion date June 1, 2024

Study information
Verified date November 2023
Source Sheikh Zayed Medical College
Contact Dr.amna Sarwar, Fcps
Phone 03218337129
Email Dr.amnasabir@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Comparison of I/V nalbuphine versus I/V xylocain in attanuation of pressor response during intubation and laryngeoscopy in patients undergoing for thyroid surgery,selection of better supressor agent minimises the drug repated side effects like hypertention tachycardia but also helps in heamodynamically stability at induction.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 60
Est. completion date June 1, 2024
Est. primary completion date March 1, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria: - middle age(18_40) - Asa 1 and 2 - Non hypertensive - Thyroid patients - patient who gives consent Exclusion Criteria: - hypertensive - Asa 3 and 4 - Patient refusal

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Lignocaine
Inj lignocain and inj nalbuphine given to two groups of participants and effects of both drugs

Locations
Country Name City State
Pakistan Dr.amna Rahim Yar Khan Punjab

Sponsors (1)
Lead Sponsor Collaborator
Sheikh Zayed Medical College

Country where clinical trial is conducted

Pakistan, 

Outcome
Type Measure Description Time frame Safety issue
Primary Reduce stress response during intubation and hemodynamic stabilty Assesment of Hemodynamic stability by observing vital signs 10 minutes
Primary Achieve hemodynamic stabilty and smooth intubation Assesment of hemodynamic stability by clinical examination of vital signs 10 minutes
See also
  Status Clinical Trial Phase
Recruiting NCT05877690 - Selective Spinal Anaesthesia With Hyperbaric Prilocain With 2%Provides Better Perioperative Hemodynamic Stability for Patients With Peripheral Vascular Disease and Cardiac Dysfunction in Lower Limb Surgery N/A
Recruiting NCT06097026 - Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular Function N/A
Recruiting NCT05706727 - Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital Phase 3
Recruiting NCT03843970 - Hemodynamic Safety of Levobupivacaine vs Bupivacaine in Patients Over 65 Years Undergoing Hip Surgery Phase 4
Completed NCT00937807 - Hemodynamic Stability During Carotid Endarterectomy.Comparison of LENOXe™ (Xenon 100% v/v) Versus Sevoflurane Phase 4
Completed NCT03734848 - Bilateral Ultrasound Guided Pectoralis Nerve Block Induces Hemodynamic Stability With Reducing Systemic Stress Response for Off-pump Coronary Artery Bypass Graft Early Phase 1
Terminated NCT02654782 - Lactated Ringer's Versus 5% Human Albumin: Cardiac Surgical Patients Phase 2
Recruiting NCT06251713 - Fluid-removal Guided by VeXUS Score With Usual Care in Patients With Acute Kidney Injury After Cardiac Surgery N/A