Hemodynamic Instability Clinical Trial
Official title:
Cardiorespiratory Effects of Nasal High Frequency Ventilation in Moderate and Late Preterm Infants With Respiratory Distress
The aim of the present work is to study the cardio-respiratory effects of non-invasive ventilation (nasal high-frequency ventilation and nasal CPAP) as an initial therapy of respiratory distress in moderate and late preterm infants as regard: I. Primary outcomes: - Duration of the non- invasive respiratory support. - Need of invasive ventilation in the first 72 hours. - Short-term complications such as air leak syndromes, pulmonary hemorrhage, intraventricular hemorrhage, and nasal trauma. II. Secondary outcomes: - Need for surfactant administration. - Days on invasive mechanical ventilation. - Days on supplemental oxygen. - Duration of hospital stay. - Mortality rate. III. Hemodynamic changes during the period of non-invasive ventilation.
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