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Hemodialysis Complication clinical trials

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NCT ID: NCT05930964 Completed - Clinical trials for Chronic Kidney Diseases

Validity of Low Physical Activity Questionnaire (LoPAQ)

Start date: April 26, 2023
Phase:
Study type: Observational

The goal of this observational study is to assess validity and reliability of Persian Version of Low Physical Activity Questionnaire. The main questions it mains to answer are: What is the level of physical activity in hemodialysis patients? Is Persian Version of Low Physical Activity Questionnaire, Valid to assess physical activity levels of dialysis patients? Is Persian Version of Low Physical Activity Questionnaire, reliable? Participants will answer 3 questionnaires and will do some functional tests.

NCT ID: NCT05922696 Completed - Anemia Clinical Trials

Cholecalciferol Supplementation in Hemodialysis Patients

Start date: May 15, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

This is prospective single-blind randomized study, in Ain Shams University hospital) in Egypt, to assess the impact of Cholecalciferol on Anemia status in regular hemodialysis outpatients

NCT ID: NCT05887960 Not yet recruiting - Clinical trials for Hemodialysis Complication

Impact of Neutrophil Lymphocyte and Monocyte Lymphocyte Ratio on Chronic Kidney Disease Patients Outcome

Start date: June 1, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to establish NLR, MLR as a good predictors for outcome of CKD including hemodialysis and CKD stage (4-5) patients as regard inflammation, malnutrition and anemia on cardiovascular complication.

NCT ID: NCT05874557 Not yet recruiting - Clinical trials for Hemodialysis Complication

A Study of Compound Amino Acid Capsule on Maintenance Hemodialysis Patients

Start date: June 2023
Phase:
Study type: Observational

The goal of this retrospective cohort study is to investigate the effects of compound amino acid capsule on nutrition, calcium and phosphorus metabolism in maintenance hemodialysis(MHD) patients. The main questions it aims to answer are: 1. Can compound amino acid capsule improve the nutritional status of MHD patients? 2. Can compound amino acid capsule help to correct the calcium and phosphorus metabolism imbalance of MHD patients? 3. Is compound amino acid capsule safe for MHD patients? We will collect the medical history and laboratory data of MHD patients who regularly took compound amino acid capsule for 9 months or did not use the same preparation in previous medical experience. We focus on the difference of serum albumin level between the treatment group and the control group within 9 months, as well as prealbumin, hemoglobin, ferritin, calcium, phosphorus, 1,25-OH 2-D3 and intact parathyroid hormone (iPTH).

NCT ID: NCT05874219 Completed - Clinical trials for Hemodialysis Complication

Mupirocin 2% Ointment Vs Spray Antibiotics on Temporary Hemodialysis Catheter

Start date: April 10, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

In dialysis centers, many patients are undergoing hemodialysis simultaneously, which facilitates the spread of microorganisms by direct or indirect contact through the devices, equipment, surface contact, and hands of health profession Over time, catheters are prone to higher rates of infection, thrombosis, and central venous stenosis, it has also been shown that catheters are an independent (of infection) inflammatory stressor and lead to increased morbidity . Catheters are aptly referred to as a bacterial highway, and a biofilm formation around the catheter is often the breeding ground of bacteria and fungi, which can easily spread to the bloodstream Infectious complications are the most serious with regards to patient morbidity and mortality. The incidence could be from 3.8 to5.5 episodes per 1000 days Migration of micro-organism along the external surface of the catheter is probably the most common route of infection through skin and represents 58% .HD catheter has biofilm formation on their surfaces and this serves as a good reservoir for micro-organisms Most patients with end stage renal disease (ESRD) starting hemodialysis through hemodialysis catheter about 9 % in Egypt and most of them require several hemodialysis catheters before maturation of arterio -venous fistula and even after stopping it.

NCT ID: NCT05872984 Completed - Clinical trials for Hemodialysis Complication

Evaluation of Total Blood Volume Measurement During Dialysis on the Incidence of Intradialytic Hypotension

Start date: July 9, 2020
Phase: N/A
Study type: Interventional

Establishing the euvolemic state in hemodialysis patients -the so called "dry weight"- is an important clinical conundrum in every nephrologist's daily practice. Underestimation of dry weight (with excessive ultrafiltration) results in dialysis-induced hypotension. Currently used methods to establish dry weight, including clinical assessment, bio-impedance spectroscopy and online relative blood volume (RBV) measurements, all have their limitations. RBV measurement reflects changes in blood volume during dialysis without providing any information about the initial hydration status, or the initial absolute blood volume (ABV). Recently, researchers proposed a new method to calculate ABV, by using the principle of dilution-indicator with RBV measurement. In a small cohort study they identified a total blood volume threshold of 65 millilitres per kilogram dry weight predicting for intra-dialytic hypotension associated symptoms. The goal of current clinical trial is to re-investigate the accuracy of the above-described method and to confirm the hypothesis of a critical threshold of 65 ml blood volume per kg dry weight in haemodialysis patients. Researchers will compare adjustment of dry weight based on the ABV measurement with standard care to see if dialysis-induced hypotension will be reduced.

NCT ID: NCT05837988 Not yet recruiting - Clinical trials for Hemodialysis Complication

Construction of Symptom Network in Maintenance Hemodialysis Patients

Start date: May 8, 2023
Phase:
Study type: Observational

Through a cross-sectional questionnaire survey, a general information questionnaire and Dialysis Frequency, Severity, and Symptom Burden Index were used to investigate the frequency, severity, and degree of symptom distress in MHD patients, and to analyze the differences in symptom distress status between long and short dialysis age MHD patients. Using the R 4.2.2 software qgraph package, construct symptom networks for MHD patients of long and short dialysis age through network analysis. Analyze network centrality indicators, including intensity, closeness centrality, and mediation centrality, to identify core symptoms and compare if there are any differences between the two groups, aiming to lay the foundation for precise and efficient phased symptom management.

NCT ID: NCT05817799 Recruiting - Clinical trials for Hemodialysis Complication

Impact of Hemodialysis on Plasma Carnitine Levels in Patients With End Stage Renal Disease

Start date: January 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

OBJECTIVES - To assess the levels of plasma carnitine in controls and hemodialysis patients. - To give supplementary L-carnitine to study subjects for a duration of 5months. - To compare the values of plasma carnitine before and after L carnitine supplementation. - To assess the role of carnitine supplementation on biochemical and clinical parameters.

NCT ID: NCT05809765 Completed - Clinical trials for Hemodialysis Complication

Effect of Triflow Breathing Training

Start date: May 16, 2020
Phase: N/A
Study type: Interventional

This study aims to explore whether an 8-week Triflow breath training program reduced the anxiety levels and improved the heart rate variability and quality of life of patients receiving hemodialysis. To investigate the effect of the triflow respiration training on the improvement of heart rate variability, anxiety, and the quality of life in hemodialysis patients.

NCT ID: NCT05743998 Completed - Clinical trials for Chronic Kidney Diseases

Inactivity and Quality of Life in Dialysis Patients

Start date: February 28, 2023
Phase:
Study type: Observational

The goal of this observational study is to compare hemodialysis and peritoneal dialysis patients. The main questions it mains to answer are: - What is the level of physical activity in hemodialysis and peritoneal dialysis patients? - What is the level of quality of life of hemodialysis and peritoneal dialysis patients? - Is there any relation between inactivity and quality of life in hemodialysis and peritoneal dialysis patients? Participants will answer 2 questionnaires and will do some functional tests.