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Metoprolol Treatment for Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T Cells

Solid Tumor Clinical Trial

Official title:
Metoprolol for the Treatment of Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T Cells

Clinical Trial Summary

The aim of this prospective study is to evaluate the feasibility and efficacy of metoprolol, a beta-1 adrenergic receptor blocker, in the treatment of cytokine release syndrome (CRS) caused by chimeric antigen receptor T (CAR T) cell infusions, its effects on the serum levels of Interleukin-6 (IL-6) and other cytokines.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04082910
Study type Interventional
Source Chinese PLA General Hospital
Contact Weidong Han, M.D.
Phone +861066939711
Email hanwdrsw@sina.com
Status Recruiting
Phase Phase 1/Phase 2
Start date September 15, 2019
Completion date December 30, 2023
View Details
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