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Clinical Trial Summary

Hepatic hemangioma is one of the most common benign tumor of the liver. Although the overall prognosis is good, active interventions are still needed in high-risk patients. Without specific drugs, the main treatment methods include surgical treatments, interventional therapies and radiotherapies. Effective medical treatments are needed urgently. Propranolol has achieved good results in infantile Facial/hepatic hemangioma, and shows some effectiveness in adult hemangioma. Here, investigators intend to evaluate the therapeutic effect of propranolol in adult hepatic hemangioma.


Clinical Trial Description

In view of the lack of medical treatment for hepatic hemangioma, investigators chose hemangioma patients with a diameter of 5-10 cm and no significant risk of rupture, or those with surgical indications but rejected of surgical, interventional/radiological interventions. After confirmation of no high risk for drugs, oral propranolol was given. The tumor size, objective remission rate, disease control rate, drugs related side effects and other endpoints events were recorded and analyzed, to assess the propranolol could or couldn't effectively control the progress of hepatic hemangioma. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03633747
Study type Interventional
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact Tingbo Liang, MD PhD
Phone 8613666676128
Email liangtingbo@zju.edu.cn
Status Recruiting
Phase Phase 1/Phase 2
Start date July 1, 2018
Completion date December 31, 2024

See also
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Completed NCT04669314 - Surgical Approach in Liver Hemangiomas