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Hemangioendothelioma clinical trials

View clinical trials related to Hemangioendothelioma.

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NCT ID: NCT04409691 Not yet recruiting - Clinical trials for Kaposiform Hemangioendothelioma (KHE) With Kasabach-Merritt Phenomenon (KMP)

SCMC Trial on KHE With KMP (V.2020)

SCMC-KK2020
Start date: July 1, 2020
Phase: Phase 1
Study type: Interventional

a phase I trial focusing on safety and efficacy of prednison shock plus sirolimus maintenance in treating Kaposiform hemangioendothelioma (KHE) with Kasabach-Merritt phenomenon (KMP)

NCT ID: NCT04406870 Not yet recruiting - Clinical trials for Hemangioendothelioma of Liver

Sirolimus in the Treatment for Infantile Hepatic Hemangioendothelioma(IEEH)

PRL-SRL-IHHE
Start date: July 2020
Phase: Phase 4
Study type: Interventional

Infantile hepatic hemangioendothelioma (IHHE) is an infantile hemangioma involving the liver.Since 2008, propranolol has been used for the treatment of hemangioma, and some researchers have also started to report the use of propranolol for the treatment of infantile hepatic hemangioma in children. Sirolimus can be used in patients with vascular malformations such as hemangiomas. IHHE is also an infantile hemangioma involving the liver,thus sirolimus may paly the role in treatment of IHHE.The clinical trial explores the efficacy of sequential treatment of sirolimus to refractory IHHE patients resistant with propranolol, to improve the therapeutic effect, reduce the side effects of traditional treatment methods (hormones, interferon), and reduce the number of operations and interventions and to provide a clinical basis for the application of the new therapeutics model of IHHE of "propranolol + sequential sirolimus treatment".