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Clinical Trial Summary

The study will evaluate the eradication rate and tolerability of modified LOAD regimens (three antibiotics and a proton pump inhibitor (lansoprazole)) for management of HP infection in treatment-naive patients as well as patients who failed previous therapies.

Clinical Trial Description

This will be randomized, parallel group, comparative open-label study that will be conducted to evaluate the efficacy and tolerability of a four-drug regimen (modified LOAD regimen) in eradicating HP. The study will evaluate the efficacy of modified LOAD regimens(levofloxacin/moxifloxacin, nitazoxanide, doxycycline and lansoprazole) inpatients who failed previous therapies and compare these regimens with the classic triple therapy (amoxicillin, clarithromycin and lansoprazole) in treatment naïve patients. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05184491
Study type Interventional
Source National Liver Institute, Egypt
Contact Gasser I El-Azab, M.D.
Phone 01280250026
Email [email protected]
Status Recruiting
Phase Phase 4
Start date October 15, 2021
Completion date March 15, 2022

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