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Nitazoxanide and Lansoprazole Based Regimens for H. Pylori Management — NILE  

Helicobacter Pylori Clinical Trial

Official title:
Nitazoxanide and Lansoprazole Based Regimens for Managing Helicobacter Pylori in Egyptian Patients (NILE Study)

Clinical Trial Summary

The study will evaluate the eradication rate and tolerability of modified LOAD regimens (three antibiotics and a proton pump inhibitor (lansoprazole)) for management of HP infection in treatment-naive patients as well as patients who failed previous therapies.

Clinical Trial Description

This will be randomized, parallel group, comparative open-label study that will be conducted to evaluate the efficacy and tolerability of a four-drug regimen (modified LOAD regimen) in eradicating HP. The study will evaluate the efficacy of modified LOAD regimens(levofloxacin/moxifloxacin, nitazoxanide, doxycycline and lansoprazole) inpatients who failed previous therapies and compare these regimens with the classic triple therapy (amoxicillin, clarithromycin and lansoprazole) in treatment naïve patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05184491
Study type Interventional
Source National Liver Institute, Egypt
Contact Gasser I El-Azab, M.D.
Phone 01280250026
Email g.elazab@gmail.com
Status Recruiting
Phase Phase 4
Start date October 15, 2021
Completion date March 15, 2022
View Details
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