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Helicobacter Pylori clinical trials

View clinical trials related to Helicobacter Pylori.

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NCT ID: NCT05790512 Completed - Helicobacter Pylori Clinical Trials

Association of Oral Helicobacter Pylori Infection With Gastric Helicobacter Pylori Infection

Start date: November 22, 2022
Phase:
Study type: Observational

The aim of this study was to investigate the association between oral Helicobacter pylori infection and gastric Helicobacter pylori infection. Patients who were tested for gastric Helicobacter pylori were tested for oral Helicobacter pylori at the same time, and were divided into four groups according to the test results to compare the positive rate of oral Helicobacter pylori.

NCT ID: NCT05635942 Completed - Helicobacter Pylori Clinical Trials

Optimized-dose Amoxicillin Versus Standard-dose Amoxicillin for Quadruple Therapy in Helicobacter Pylori Eradication

Helicomatri
Start date: January 29, 2019
Phase: Phase 4
Study type: Interventional

The goal of this prospective randomized clinical trial is to compare the rate of Helicobacter Pylori (HP) eradication after standard or dose-optimized amoxicillin quadritherapy in patients naïve to any anti-HP treatment and with chronic HP infection documented by histological examination. The main questions it aims to answer are: - compare the eradication rate of H.Pylori after a standard concomitant quadritherapy with 2g of amoxicillin versus an optimized quadritherapy with 3g of amoxicillin, in Tunisian population - Identify different factors associated with poor therapeutic response Patients were randomly assigned to either standard quadruple therapy (Qs-14: amoxicillin 1g twice daily, clarithromycin 500mg twice daily, metronidazole 500mg twice daily and esomeprazole 40mg twice daily for 14 days), or optimized quadruple therapy (Qo-14: amoxicillin 1g three times a day, clarithromycin 500mg twice daily, metronidazole 500mg twice daily and esomeprazole 40mg twice daily for 14 days). Eradication control was performed by urea breath test.

NCT ID: NCT05073367 Completed - Helicobacter Pylori Clinical Trials

A Study Reviewing Medical Records of Adults With Helicobacter Pylori Infections in China

Start date: September 21, 2022
Phase:
Study type: Observational

The main aim of the study is to review treatment therapies in people with Helicobacter pylori (H. pylori) infections in standard hospital settings in China. In this study, the study doctors will review medical records of participants who have had H. pylori infections any time from 1st January 2019 to 31st December 2021. This study is about collecting existing data only; participants are not treated and do not need to visit a study doctor during this study.

NCT ID: NCT04810793 Completed - Helicobacter Pylori Clinical Trials

The Study on the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure

Start date: July 1, 2020
Phase:
Study type: Observational [Patient Registry]

The patients who accepted the quadruple eradication program of the helicobacter pylori but failed to eradicate helicobacter pylori will be assessed the most suitable re-eradication time of helicobacter pylori.

NCT ID: NCT04753437 Completed - Helicobacter Pylori Clinical Trials

A Study of Vonoprazan in Adults With Helicobacter Pylori

Start date: April 6, 2021
Phase: Phase 1
Study type: Interventional

Helicobacter Pylori (H Pylori) is a bug found in the digestive system. It can cause soreness and redness in the stomach (gastritis). It can also cause ulcers in the stomach and other parts of the digestive system. Vonoprazan is a medicine to treat people with H Pylori. It is taken together with other medicines to fight infections caused by H Pylori. The main aim of this study is to learn if vonoprazan changes how the other medicines are processed by the body. It will be compared with another medicine called esomeprazole. Other aims are to check for side effects from the study medicines. At the first visit, the study doctor will check who can take part. Participants who take part will be picked for 1 of 2 treatments by chance. - Vonoprazan taken with bismuth, clarithromycin, and amoxicillin - Esomeprazole taken with bismuth, clarithromycin, and amoxicillin Both treatments will last for 14 days. Participants will stay in the clinic throughout their treatment. After treatment, the clinic staff will telephone the participants 2 days later for a check-up. The participants will visit the clinic 4 weeks later for a final check-up.

NCT ID: NCT04198363 Completed - Helicobacter Pylori Clinical Trials

A Study to Evaluate the Efficacy and Safety of Bismuth-Containing Quadruple Therapy With Oral Vonoprazan (TAK-438) 20 mg Compared to Esomeprazole 20 mg Twice Daily in Paticipants With Helicobacter Pylori Infection

Start date: April 30, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of helicobacter pylori (HP) eradication with bismuth-containing quadruple therapy with vonoprazan versus esomeprazole in all HP-positive participants.

NCT ID: NCT03716622 Completed - Helicobacter Pylori Clinical Trials

A Comparison of Clarithromycin-based and Furazolidone-based Bismuth-containing Regimens for H. Pylori Eradication

Start date: July 31, 2018
Phase: Phase 4
Study type: Interventional

We aim to assess and compare the effectiveness of clarithromycin- and furazolidone-based regimens as primary therapies in eradicating H. pylori.

NCT ID: NCT03566004 Completed - Helicobacter Pylori Clinical Trials

Performances of a H. Pylori Stool PCR Test

HEPYSTOOL
Start date: December 10, 2015
Phase: N/A
Study type: Interventional

Performance of a non-invasive test for the detection of Helicobacter pylori and its resistance to clarithromycin in stool by Real-Time PCR Amplidiag H. pylori + ClariR (Mobidiag).

NCT ID: NCT02892409 Completed - Helicobacter Pylori Clinical Trials

TAK-438 Bismuth Drug Interaction Study

Start date: September 5, 2016
Phase: Phase 1
Study type: Interventional

To evaluate the safety, tolerability, and pharmacokinetics (PK) of quadruple therapy with bismuth, clarithromycin, amoxicillin, and TAK-438 versus quadruple therapy with bismuth, clarithromycin, amoxicillin, and lansoprazole.

NCT ID: NCT01667575 Completed - Clinical trials for Functional Dyspepsia

Efficiency Study of Clarithromycin and Bismuth-containing Quadruple Therapy to Treat H.Pylori

Start date: August 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to observe the efficacy of ten day triple therapy-based, bismuth-containing quadruple therapy for H.pylori treatment.