Helicobacter Pylori Infection Clinical Trial
Official title:
A Study on Eradication Rate of Triple Therapy Including Low Dose-PPI, Clarithromycin, Amoxicillin According to Treatment Period and CYP2C19 Polymorphisms in H.Pylori Patients
This study compared efficacy and safety of basic triple therapy according to treatment period. This study evaluated Effect of CYP2C19 genetic polymorphisms on the efficacy
This study compared efficacy and safety of basic triple therapy including Noltec(Ilaprazole)
10mg, Clapaxine(Clarithromycin) 500mg and Pamoxin Cap(Amoxicillin) 1000mg BID on the first
line eradication treatment of H.pylori according to treatment period.
Participants are defined as persons who have endoscopically confirmed on gastric or duodenal
ulcer(including scar stage) and gastritis confirmed to be H.pylori positive patients in the
UBT test. For 7 days or 10 days Participants treated as basic triple therapy including
Noltec(Ilaprazole) 10mg, Clapaxine(Clarithromycin) 500mg and Pamoxin Cap(Amoxicillin) 1000mg
BID. After treatment, The healing rate was evaluated in the UBT test at 49±5days from the
first day dosing. The investigators would point out the impact of CYP2C19 genotypes on
Clarythromycin-based first-line and rescue therapies.
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