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Safety and Efficacy Study of a Non-antibiotic Treatment for the Eradication of Helicobacter Pylori

Helicobacter Pylori Infection Clinical Trial

Official title:
A Single-centre, Open-label, Non-controlled, Exploratory Safety and Efficacy Clinical Trial of GT08 in Volunteers and Patients Who Are Infected With Helicobacter Pylori

Clinical Trial Summary

At present, triple therapy is recommended by various guidelines for the treatment of Helicobacter pylori (H.pylori) infection. Recent studies have shown increasing resistance of H.pylori to commonly used antibiotics used in triple therapy. This study explores a non-antibiotic treatment regime for H.pylori that uses lauric acid as the primary anti-microbial agent. The study hypothesis is that Lauric acid works synergistically with omeprazole following administration of a mucolytic agent to kill H.pylori topically in the stomach.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01109381
Study type Interventional
Source Synergy Pharmaceuticals Pte. Ltd.
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date May 2010
Completion date December 2011
View Details
See also
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