Helicobacter Pylori Infection Clinical Trial
Official title:
Phase 4 Study of Helicobacter Pylori Eradication Therapy
The role of Helicobacter pylori infection in functional dyspepsia remains controversial.
Several randomized controlled trials in western countries have shown no significant
advantage over placebo. But some recent studies in Asian population were different compared
to the result of studies in the Western population. At the present time, it seems to be
difficult to conclude the efficacy of the H.pylori eradication therapy in patients with H.
pylori-infected functional dyspepsia.
The investigators hypothesize that eradication of Helicobacter pylori has a sustained global
symptom improvement in patients with H. pylori infected functional dyspepsia.
Functional dyspepsia: diagnosed by Rome III criteria of Functional gastrointestinal disorder Treatment regimen: Combination of proton pump inhibitor, Amoxicillin, Clarithromycin for 7 days Placebo: Same shaped placebo drugs ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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