Efficacy on Helicobacter Pylori Eradication With Two Antibiotic Regimens

Status Completed

Clinical Trial Summary

Clinical trial to compare efficacy on eradicating Helicobacter pylori with two antibiotic strategies: sequential with amoxicillin and omeprazole 5 days and clarithromycin with metronidazole and omeprazole 5 days or omeprazole with clarithromycin and amoxicillin 14 days.

Clinical Trial Description

In patients with documented infection with Helicobacter pylori after endoscopy and biopsy, two modalities of treatment were compared, and after a control endoscopy and biopsy, eradication was assessed as well as side effects of both treatments. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Helicobacter Infections

Clinical Trial Details

NCT number	NCT02395458
Study type	Interventional
Source	Coordinación de Investigación en Salud, Mexico
Contact
Status	Completed
Phase	Phase 4
Start date	March 2013
Completion date	February 2015

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT00723502` - Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected Patients	Phase 2
Recruiting	`NCT03365609` - A Comparison of Four Different Treatment Regimens of Helicobacter Pylori in Chinese Children	N/A
Completed	`NCT00005496` - Inflammation, Infection, and Future Cardiovascular Risk	N/A
Completed	`NCT01219764` - A Trial of Standard vs Half Dose Rabeprazole, Clarithromycin, Metronidazole and Amoxicillin in the Treatment of Helicobacter Pylori Infection	Phase 4
Completed	`NCT00216450` - Study of the Safety and Effectiveness of Rabeprazole in Treatment of Helicobacter Pylori Infection in Adults.	Phase 4
Completed	`NCT00212225` - Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)	N/A
Completed	`NCT00083291` - Helicobacter Pylori and Dry Eye	N/A
Not yet recruiting	`NCT04652284` - Effectiveness of Rifabutin for Treatment of Helicobacter Pylori	Phase 3
Completed	`NCT02449941` - Helicobacter Pylori and Proton Pump Inhibitor	N/A
Completed	`NCT00194688` - Breath Ammonia Method for H. Pylori Detection: Phase II	Phase 2
Not yet recruiting	`NCT02126722` - Endofaster Test for Helicobacter Pylori Detection in Patients on Proton Pump Inhibitor Therapy	N/A
Active, not recruiting	`NCT01133951` - Helicobacter Pylori Eradication to Prevent Gastric Cancer	N/A
Completed	`NCT00669955` - Efficacy and Safety of Quadruple Therapy in Eradication of H. Pylori: A Comparison to Triple Therapy	Phase 3
Completed	`NCT00816140` - Levofloxacin Versus Clarithromycin Triple Therapy in First-Line Treatment for Helicobacter Pylori Eradication	Phase 4
Completed	`NCT00490386` - Helicobacter Pylori and Acute Alcohol Induced Pancreatitis	N/A
Withdrawn	`NCT02645201` - The Effect of Probiotic Combination on Helicobacter Pylori Infection in Children	N/A
Terminated	`NCT00664209` - Treating H. Pylori in Parkinson's Patients With Motor Fluctuations	Phase 3
Completed	`NCT01922505` - Eradication Rates of Helicobacter Pylori and Its Affecting Factors	Phase 4
Completed	`NCT01792700` - Long-term Follow up Helicobacter Pylori Reinfection Rate After Second-Line Treatment: Bismuth-Containing Quadruple Therapy Versus Moxifloxacin-Based Triple Therapy	Phase 4
Completed	`NCT02970110` - Specimen Collection Study for H. Pylori Testing