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Heavy Drinking clinical trials

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NCT ID: NCT05398315 Completed - Heavy Drinking Clinical Trials

Interactive Alcohol Decision-Making Programs

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

This project aims to develop a maximally effective, computer-delivered brief intervention (CDBI) for reducing heavy alcohol use. More specifically, the investigators will examine outcomes of different versions of a CDBI in which the presence/absence of empathic statements, the gender of the narrator, the presence/absence of a narrator backstory, and the use/non-use of motivational interviewing techniques are systematically manipulated using a factorial design. Participants (352 heavy drinkers) will be randomly assigned to 1 of 16 intervention conditions, representing all combinations of the 4 variables being manipulated. The investigators hypothesize that there will be significant main effects of all four factors being manipulated on (a) subjective reactions to the CDBI and (b) alcohol outcomes at 1-month follow-up

NCT ID: NCT05189379 Completed - Heavy Drinking Clinical Trials

Targeted Extinction of Drug Cues During Sleep - Olfactory Cue Reactivity Task

TEDDS_OCRT
Start date: March 10, 2022
Phase: N/A
Study type: Interventional

The study aims to utilise olfactory stimulation in addition to the visual stimulation in cue reactivity tasks to enhance precision in measuring alcohol based cues in individuals diagnosed with heavy drinking. The study consists of one cue reactivity task with visual stimuli, another cue reactivity task with matching odour/visual stimuli and lastly a monetary incentive delay task.

NCT ID: NCT05090995 Completed - Heavy Drinking Clinical Trials

A PPG Sensor-Based Feedback Intervention for Heavy Drinking Young Adults

Start date: February 23, 2022
Phase: N/A
Study type: Interventional

Heavy alcohol use among young adults is a significant public health problem. Advances in technology may offer an innovative solution. This project will conduct the first controlled test of a feedback intervention for reducing drinking and improving health in young adults by targeting heart rate variability, resting heart rate, and sleep via biosensors and electronic diary methods.

NCT ID: NCT04710095 Completed - Heavy Drinking Clinical Trials

Perceived Alcohol Rewards and Risks Study

PARS
Start date: November 13, 2015
Phase: N/A
Study type: Interventional

The identification of mechanisms that underlie how people reduce or eliminate alcohol use is a critical public health issue. Understanding these mechanisms can inform how to effectively intervene with problem drinkers. Thus far it has been a challenge for the alcohol research field to find consistent empirical evidence in support of candidate mechanisms of behavior change. Scientific advancement in this area may be aided by longitudinal transdisciplinary research on the interplay between behavioral intervention, cognition, and brain activity to understand underlying processes of behavior change among heavy drinkers. This study employed a randomized 2-arm repeated measures design with a sample of non-treatment seeking adult heavy drinkers to examine changes in perceived reward value and risks of alcohol use as a mechanism of alcohol behavior change after a brief behavioral intervention. Participants were randomized to either a 1-session behavioral intervention or to an attention-matched control condition and immediately after completed an fMRI scan. The focus of this project is to examine if group differences in perceived alcohol reward value after the intervention mediates an intervention effect on reducing alcohol use in the 1 month following the intervention.

NCT ID: NCT04639882 Completed - Heavy Drinking Clinical Trials

Motivating Recruitment and Efficacy in Normative Feedback Interventions

Start date: September 10, 2014
Phase: N/A
Study type: Interventional

Excessive alcohol consumption among college students continues to be a serious public health concern associated with a wide range of negative consequences. Brief computer-based social norms interventions, including personalized normative feedback (PNF), have shown consistent effects in reducing problematic drinking in this population, and there is some evidence that in-lab computer-delivered interventions may be more effective than remote interventions. Most studies have been conducted using generous incentives which may reduce the feasibility of dissemination on a larger scale and may undermine trial efficacy. In accordance with NIAAA aims, this research aims to (a) investigate delivery modality (i.e., in lab versus remotely) and incentives as important factors affecting the efficacy of PNF interventions and (b) develop intervention strategies that facilitate wider dissemination of inexpensive empirically-supported brief interventions for college students, thereby reducing problem drinking during a high-risk time period.

NCT ID: NCT04275739 Completed - Heavy Drinking Clinical Trials

Brief Academic Future Thinking Intervention for College Student Drinkers

Start date: January 20, 2018
Phase: N/A
Study type: Interventional

The present study investigated the feasibility, acceptability, and initial utility of a brief academic goal-relevant episodic future thinking (A-EFT) task among heavy college drinkers. First, the study attempts to extend the temporal reach of EFT interventions which have demonstrated immediate reductions in discounting, and alcohol demand. The current study utilized a longitudinal design to evaluate whether EFT can change drinking behavior outside the lab in heavy drinking college students. The two-group experimental design included an active control group, weekly booster contact, and 1-month follow-up. Second, this study seeks to investigate whether the process of engaging in EFT is sufficient to produce effects when cues are not presented during the decision-making task. Lastly, this study adds an academic goal-related focus to the EFT task based on previous research indicating that forming meaningful academic goals is protective against drinking and associated problems.

NCT ID: NCT04075773 Completed - Heavy Drinking Clinical Trials

Brief Religious Alcohol Intervention

BRAI
Start date: September 4, 2019
Phase: N/A
Study type: Interventional

This study is a trial of a brief alcohol intervention, a brief expressive writing intervention that incorporates religious identity.

NCT ID: NCT03274167 Completed - Alcohol Drinking Clinical Trials

Efficacy of Gabapentin in Alcohol Dependency Treatment

Start date: January 2012
Phase: Phase 3
Study type: Interventional

The study aims to study the effect of gabapentin on the number of alcohol drinking days and heavy drinking days in the Thai clinical alcohol-dependent population by using the double-blinded randomized controlled approach. One-hundred and twelve individuals with alcohol dependence were randomly assigned equally into two groups including treatment with gabapentin and placebo. Thirty-four patients (30.3%) completed the study protocol, i.e. treatment with gabapentin at least 300 mg per day or placebo orally once a day for twelve weeks. Pattern of alcohol drinking were obtained from the timelime followback. Drinking behaviors were compared between the two groups by poisson repeated measures model.

NCT ID: NCT03159468 Completed - Heavy Drinking Clinical Trials

Emotion Regulation Interventions for Alcohol-Related Sexual Aggression

Start date: December 31, 2016
Phase: N/A
Study type: Interventional

Rates of sexual assault are alarmingly high, and alcohol is consistently implicated in the majority of these assaults. Despite well-intentioned prevention efforts, this pandemic continues unabated, warranting the development of novel and innovative approaches to the reduction of sexual aggression. The goal of this research is to evaluate the efficacy of two brief online emotion regulation interventions for reducing alcohol-related sexual aggression in heavy episodic drinking young men with a sexual aggression history. Previous research suggests that emotion regulation difficulties are associated with both alcohol consumption and aggressive behavior. Despite the potential prevention utility of improving sexually aggressive men's emotion regulation skills in order to reduce their alcohol-related sexual aggression, this approach has yet to be explored. Thus, this study evaluates the effects of two brief online ER interventions - cognitive restructuring and mindfulness - on men's emotion regulation during a sexual aggression-related analogue. Additionally, these effects will be evaluated during both sober and intoxicated states through a laboratory- based alcohol administration experiment.

NCT ID: NCT03111056 Completed - Sexual Assault Clinical Trials

Web-Based Treatment of Heavy Drinking Among Women With a History of Sexual Trauma

Start date: January 2017
Phase: N/A
Study type: Interventional

The goal of this study is to empirically evaluate a web-based intervention to reduce heavy drinking among college women with a history of sexual assault who display elevated levels of psychological distress. College women with a history of sexual assault often report more heavy drinking and psychological distress than women without a history of assault. Moreover, women with assault histories often have difficulty regulating their emotions and tolerating distress which can lead to a pattern of drinking to cope distress. Trauma exposure, negative mood, and poor coping strategies have been associated with poor treatment outcomes and relapse following alcohol treatment. Incorporating distress tolerance and emotion regulation skills with an alcohol intervention may enhance treatment effects among women with a history of sexual assault by decreasing their motivation to drink to cope with depression or anxiety and by building adaptive coping strategies. Therefore, the web-based intervention will include cognitive behavioral skills for reducing alcohol consumption and incorporate emotion regulation and distress tolerance skills from Dialectical Behavior Therapy.