Symptom Control Satisfaction With Proton Pump Inhibitor Regimen

Status Completed

Clinical Trial Summary

The overall aim of this study is to assess if patients with persistent gastroesophageal reflux disease (GERD) symptoms receiving sub-optimal omeprazole dosing experience improvement in GERD symptoms when prescribed an optimal dosing regimen. The optimal dosing regimen is defined as taking omeprazole 30 minutes prior to the first meal of the day.

Clinical Trial Description

GERD remains a common gastrointestinal complaint, resulting in 6% of outpatient visits. The economic burden is significant with direct costs exceeding $12 billion/year and indirect cost as high as $75 billion/year. The primary aim of this study was determine whether a brief educational intervention optimizing proton pump inhibitor (PPI) dosing would reduce GERD symptoms using the gastroesophageal reflux disease symptom assessment scale (GSAS) questionnaire. Further, secondary analysis would utilize the results of the trial and combine them with costs related to uncontrolled GERD to estimated the potential economic impact. ;

Study Design

Related Conditions & MeSH terms

Heartburn

Clinical Trial Details

NCT number	NCT02623816
Study type	Interventional
Source	MetroHealth Medical Center
Contact
Status	Completed
Phase	Phase 4
Start date	August 2014
Completion date	December 2015

View Details

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