Heart Valve Diseases Clinical Trial
Official title:
SEP-study; The Assessment of Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Organic Mitral Valve Regurgitation
Surgical treatment is the only approach with potentially defined clinical success for
organic mitral valve (MV) regurgitation. Recurrent or persistent complaints after initial
successful MV repair is a clinical challenge in current practice. Especially when echo
parameters at rest are within or near normal ranges and patients presenting
disproportionately symptomatic in relation to the observed results. However, while MV
regurgitation is a hemodynamic disease, currently used 2-dimensional (2D) transthoracic
echocardiography (TTE) at rest lacks information about hemodynamic changes. Physical stress
echocardiography is a promising technique to complement nowadays rest TTE in order to
improve interpretation of hemodynamic changes. However, normal values for exercise echo are
lacking in this postoperative patients cohort. A prospective, observational trial to
determine normal values in stress echocardiographic parameters in asymptomatic patients
after successful MV repair for organic MV regurgitation, is therefore highly needed.
Purpose of the SEP- study is to determine normal values in stress echocardiographic
parameters in asymptomatic patients at least 6 months after successful MV repair for organic
MV regurgitation. These normal values for stress echo are of utmost importance to correctly
and accurate interpret stress echo results during postoperative follow-up and to improve
clinical decision making in patients post MV repair.
n/a
Time Perspective: Cross-Sectional
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