Heart Transplant Clinical Trial
Official title:
Effectiveness Improving Medication Adherence in Heart Transplant Management
The purpose of this study is to improve medication adherence, engagement and support to heart transplant patients through implementation of a new clinical care programme conducted by the clinical pharmacy service in cooperation with the heart transplant team and supported by mobile health (mHealth).
Non-adherence to immunosuppressive medications generally ranges from 20-40% and is
associated with acute rejection episodes and graft loss. Many solid organ transplant centres
have incorporated transplant pharmacists into the multidisciplinary transplant clinical team
focused on improving outcomes and safety associated with drug therapy.
Mobile technology has undergone rapid advances in the past several years and the use of
mHealth in pharmaceutical care is changing pharmacy practice. Several published reports have
identified general mobile applications suited for improve adherence. But evidence supporting
the benefits in clinical practice is limited.
This study expects to analyse the potential of mHealth to improve medication adherence and
heart transplant patient management in real clinical practice.
The investigators asses a new multidisciplinary follow-up programme in heart transplant
recipients supported by mobile health (mHealth) with the aim to improve medication
adherence, prevent drug related problems and improve patient clinical outcomes.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02964026 -
Study of Clinical Outcomes Associated With the Pulmonary Artery Catheter (PAC) in Cardiac Surgery Patients
|
N/A | |
| Active, not recruiting |
NCT05096299 -
OCS Heart EXPAND + CAP Continued Follow-Up
|
||
| Completed |
NCT02323321 -
International EXPAND Heart Pivotal Trial
|
N/A | |
| Not yet recruiting |
NCT05025774 -
Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
|
||
| Recruiting |
NCT05933083 -
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
|
N/A | |
| Completed |
NCT03150095 -
Health Coaching to Improve Self-Management in Thoracic Transplant Candidates
|
N/A | |
| Terminated |
NCT03346278 -
Text Message Intervention to Improve Cardiac Rehab Participation
|
N/A | |
| Active, not recruiting |
NCT05741723 -
OCS DCD Heart + CAP Continued Follow-Up
|
||
| Completed |
NCT03831048 -
Donors After Circulatory Death Heart Trial
|
N/A | |
| Completed |
NCT04615182 -
Donor After Circulatory Death Heart CAP Trial
|
N/A | |
| Completed |
NCT02597543 -
Stress Cardiac MRI for Evaluation of Nonspecific Allograft Dysfunction
|
Phase 4 | |
| Recruiting |
NCT05824364 -
Exercise aNd hEArt Transplant
|
N/A | |
| Enrolling by invitation |
NCT05390411 -
Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies Trial
|
N/A | |
| Recruiting |
NCT04770012 -
AERIAL Trial: Antiplatelet Therapy in Heart Transplantation
|
Phase 3 | |
| Terminated |
NCT01769443 -
Safety and Efficacy of Desensitization Therapy in Sensitized Participants Awaiting Heart Transplantation
|
Phase 2 | |
| Completed |
NCT00466804 -
Noninvasive Methods to Monitor Graft Survival in Heart Transplant Patients
|
N/A | |
| Recruiting |
NCT06426173 -
Effect of Resistance Training in Patients on the Waiting List for Heart Transplant
|
N/A | |
| Not yet recruiting |
NCT05459181 -
HeartCare Immuno-optimization in Cardiac Allografts (MOSAIC)
|
N/A | |
| Terminated |
NCT01485757 -
Prospective L-arginine Study
|
Phase 1 | |
| Active, not recruiting |
NCT01186250 -
Clinical Trial of Pioglitazone for Prevention of Cardiac Allograft Vasculopathy After Heart Transplantation
|
Phase 2 |