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Heart Septal Defects, Atrial clinical trials

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NCT ID: NCT03024268 Active, not recruiting - Clinical trials for Mitral Valve Insufficiency

MitraClip® and Hemodynamic Effects of Relevant Iatrogenic Atrial Septum Defect Closure

Start date: January 2016
Phase: N/A
Study type: Interventional

Aim of this prospective trial is to assess the hemodynamic effects of a MitraClip procedure caused iatrogenic arterial septal defect (iASD) and the functional changes after interventional iASD closure in a randomized setting.

NCT ID: NCT02985684 Completed - Clinical trials for Atrial Septal Defect

Safety and Efficacy Study of Transcatheter Closure of Ostium Secundum ASDs

ASSURED
Start date: March 10, 2017
Phase: N/A
Study type: Interventional

Evaluate the safety and efficacy of the GORE® CARDIOFORM ASD Occluder in the percutaneous closure of ostium secundum atrial septal defects (ASDs)

NCT ID: NCT02957201 Completed - Clinical trials for Atrial Septal Defect

The Effect on EPCs by Successful Cardiac Occlusion Device Implantation

EPIC
Start date: July 2016
Phase: N/A
Study type: Interventional

All patients awaiting to have either a left atrial appendage closure (LAA) or patent foramen ovale (PFO) or Atrial Septal Defect (ASD) closure device as part of standard care will be identified and reviewed in cardiology clinics. These patients will be placed on waiting list to undergo the procedure. Patient-participants will be consented on the date of admission for device closure implantation. The study will recruit 20 patients divided into; 10 patients undergoing PFO/ASD closure and 10 patients undergoing LAA closure. EPC will be measured on the day of the device implantation, day 0 and prior to discharge on day 1. Patient participants are admitted overnight after the device closure implantation. Then on subsequent out patient cardiology research clinic follow appointments on days (3-4) and (7-8).

NCT ID: NCT02867930 Completed - Heart Valve Disease Clinical Trials

Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echocardiography

KDTEE
Start date: June 2016
Phase: Phase 4
Study type: Interventional

The purpose of the study is to compare dexmedetomidine and ketofol to find a suitable alternative for moderate sedation in out-patient diagnostic trans-esophageal echocardiography.

NCT ID: NCT02766569 Enrolling by invitation - Clinical trials for Atrial Septal Defect

International Registry for ASD Closure by Using the Occlutech®Flex II Device in More Than 2000 Patients

IRFACODE-II
Start date: July 2016
Phase: N/A
Study type: Observational [Patient Registry]

The IRFACODE II study will evaluate the performance and safety of the Occlutech® Flex II device in patients with closure of secundum atrial septal defects (ASD II).

NCT ID: NCT02739087 Active, not recruiting - Aortic Stenosis Clinical Trials

Radiation-Free Heart Catheterization Using MRI

Start date: March 2015
Phase: N/A
Study type: Interventional

Currently catheters used in heart catheterization procedures are guided throughout the heart chambers and blood vessels by pictures taken by x-rays. This technology exposes patients to radiation. With this study protocol the investigators will use MRI technology to take real-time pictures to navigate catheters throughout heart chambers. MRI uses electromagnetic energy; therefore, it does not expose participants to radiation energy.

NCT ID: NCT02621528 Completed - Clinical trials for Patent Ductus Arteriosus

Lifetech CeraFlex™ Post-Market Surveillance Study

Start date: October 2015
Phase: N/A
Study type: Interventional

The purpose of this multi-center, non-interventional, prospective, post-market clinical study is to collect real world data on patient outcomes and evaluate the procedural success and performance of the Lifetech CeraFlex™ occluders for patients with secundum type Atrial Septum Defect (ASD), Patent Foramen Ovale (PFO) or Patent Ductus Arteriosus (PDA).

NCT ID: NCT02601768 Recruiting - Clinical trials for Ostium Secundum Atrial Septal Defect

Occluder Size Determination in Transcatheter ASD II Closure Based on 3D TEE Assessment

Start date: January 2015
Phase: N/A
Study type: Observational

The aim of this study is to determine whether three-dimensional tranesophageal echocardiography (3D TEE) assessment of ostium secundum atrial septal defect (ASD II) may be as efficient as two-dimensional (2D) TEE assessment complemented by the balloon-sizing during transcatheter closure of the defect.

NCT ID: NCT02552485 Completed - Clinical trials for Atrial Septal Defects

Evaluation of Latent Pulmonary Arterial Hypertension in Congenital Shunt Lesions

Start date: January 2015
Phase: N/A
Study type: Observational

Prospective, monocentric study for the evaluation of latent pulmonary arterial hypertension in patients with congenital shunt lesions lost to follow-up. Lost to follow-up is defined as latest clinical control ≥ 5 years.

NCT ID: NCT02529111 Completed - Clinical trials for Atrial Septal Defects

Percutaneous Closure of Atrial Septal Defects in Children: Integration of 3D Echocardiography and Fluoroscopy Imaging.

CIA3DNAVIGATOR
Start date: December 2015
Phase: N/A
Study type: Interventional

The interventional catheterization allows the percutaneous treatment of congenital heart diseases as the atrial septal defect (ASD). The examination is guided by the X-rays with stochastic side effects worrying at the child's. The software "Echonavigator" allows to merge the ultrasound image and fluoroscopic. This innovative software facilitates the procedures and reduce the irradiation time in some adult procedures. The aim of this study was to validate the image fusion in children.