Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05334628
Other study ID # E.Kurul-E1-22-2536
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date April 11, 2022
Est. completion date October 12, 2022

Study information

Verified date October 2022
Source Ankara City Hospital Bilkent
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Video-assisted thoracic surgery (VATS) is frequently applied in thoracic surgery operations. VATS has become the standard procedure in minor and major lung surgeries. In recent years, regional anesthesia techniques have also been frequently applied to patients for pain relief. Thoracic paravertebral block (TPVB), erector spinae plane block (ESPB), and serratus anterior plane block (SAPB) are also among the regional anesthesia techniques frequently used in thoracic surgery. General anesthesia (GA) is the main method of anesthesia for thoracic surgery. However, GA can only inhibit the projection system of the cortical limbic system or hypothalamic cortex. GA cannot completely block the transmission of peripheral noxious stimulus to the central nervous system and cannot effectively inhibit the intraoperative stress response. With the addition of peripheral blocks such as TPVB, ESPB, and SAPB, more stable hemodynamics is expected by providing preemptive analgesia in patients. As a result of all these; In this study, we aimed to compare the intraoperative hemodynamic changes of patients who underwent preoperative ESPB in patients who will undergo VATS resection under GA with those who underwent postoperative ESPB.


Recruitment information / eligibility

Status Completed
Enrollment 60
Est. completion date October 12, 2022
Est. primary completion date September 12, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria: - Age between 18 and 80 years - American Society of Anesthesiologists physical status I-II-III - Body mass index between 18-40 kg/m2 - Patients undergoing elective video assisted thoracoscopic surgery Exclusion Criteria: - Advanced cancer - History of chronic analgesic therapy - History of local anesthetic allergy - Infection in the intervention area - Patients with bleeding disorders

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
Preoperative Erector spinae plane block
Erector spinae plane block will be performed unilaterally, under US guidance, before the surgical operation, after the induction of anesthesia, and when the patient is placed in the lateral decubitus position.
Postperative Erector spinae plane block
Erector spinae plane block will be performed unilaterally, under US guidance, after the surgical operation, under general anesthesia, and when the patient is placed in the lateral decubitus position.

Locations

Country Name City State
Turkey Ankara City Hospital Çankaya Ankara
Turkey Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital Keçiören Ankara

Sponsors (1)

Lead Sponsor Collaborator
Ankara City Hospital Bilkent

Country where clinical trial is conducted

Turkey, 

Outcome

Type Measure Description Time frame Safety issue
Primary Mean arterial pressure Mean arterial pressure values will be recorded before anesthesia, before surgical incision, after surgical incision at 5th, 30th, 60th, 90th, 120th minutes, and after general anesthesia. Perioperative period
Primary Heart rate Heart rate values will be recorded before anesthesia, before surgical incision, after surgical incision at 5th, 30th, 60th, 90th, 120th minutes, and after general anesthesia. Perioperative period
Secondary Pain scores Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at the 1st, 2nd, 4th, 12th, and 24th hours after surgery. First 24 hours after surgery
See also
  Status Clinical Trial Phase
Completed NCT03832205 - Validation of Respiratory Rate and Heart Rate Measurements by Capaciflectors Placed in Four Locations on the Chest
Completed NCT03723954 - Heart Rate Variations of Golf Fans During the 2018 the Ryder Cup
Withdrawn NCT01026961 - Safety of Phenylephrine Hydrochloride, Acetaminophen, Dimethindene Maleate Compared to Phenylephrine Hydrochloride Alone in Healthy Volunteers Phase 1/Phase 2
Completed NCT00760253 - Compare the Side Effects and Difference Awake Level of Three TCI Propofol Formula in TVOR Patients N/A
Completed NCT00380341 - Effects of Instrument-Applied Spinal Manipulative Therapy on Postureal Control and Autonomic Balance N/A
Completed NCT04179279 - Comparative Analysis of a Non-contact Respiratory and Heart Rate Monitor Vs. a Conventional Clinically Validated Reference Monitor
Completed NCT02469844 - Heart Rate Variability (HRV) Analysis in Patients With Nocturnal Epileptic Seizures
Not yet recruiting NCT00503282 - Urinary Catheter Exchange on Admission of Septic Elderly With Permanent Catheter Before Initiation of Antibiotics N/A
Completed NCT05160207 - Intubation-induced Decrease in Heart Rate as an Indicator for Intraoperative Bradycardia
Completed NCT02997800 - The Effect of Intraoperative Labetalol on Time to Discharge Phase 2
Withdrawn NCT01701960 - Effect of Local Anesthetic on Hemodynamic Measures During Nasal Surgery N/A
Completed NCT03359928 - Acute Physiological and Perceptual Responses to Novel Forms of High-intensity Interval Exercise N/A
Completed NCT05600725 - Novel Cardiac Pacing to Initiate Cardiac Remodeling in Heart Failure N/A
Completed NCT05366049 - The Effect of Methods Used in Oral Antipyretic Administration on the Vital Findings of the Child With Fever N/A
Recruiting NCT05401435 - Reliability of Measuring Blood Pressure With a Smartwatch N/A
Completed NCT01638169 - The Contribution of Heels for Walking Quality Among Children With Muscular Dystrophy N/A
Completed NCT00143988 - Heart Rate and Blood Pressure Response During Exercise and Sexual Activity in Normotensive and Hypertensive Volunteers N/A
Completed NCT03131375 - Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia Phase 2/Phase 3
Completed NCT01612130 - Valerian for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery N/A
Completed NCT06095635 - Acute Influence of Resveratrol Supplementation and Beet Extract in Recovery After Exercise in Coronary Paths N/A