Heart Rate Variability Clinical Trial
— MSNAOfficial title:
Effects of Non Invasive Vagus Nerve Stimulation on Heart Rate Variability in Healthy Subjects and on Muscle Sympathetic Nerve Activity
To demonstrate the effect of non invasive vagus nerve (VNS) stimulation on heart rate variability and MSNA signal.
Status | Recruiting |
Enrollment | 60 |
Est. completion date | December 2019 |
Est. primary completion date | December 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Healthy volunteers - >18 years old Exclusion Criteria: - pregnancy and breastfeeding - smoke - alcool/energy drinks/coffee consumption, exertion 24h before the participation |
Country | Name | City | State |
---|---|---|---|
Belgium | Erasme University Hospital | Brussels |
Lead Sponsor | Collaborator |
---|---|
Université Catholique de Louvain | Erasme University Hospital |
Belgium,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Profile of response of MSNA during prolonged breath hold | Modulation of MSNA activity during repetitive prolonged breath hold | 4hours | |
Primary | Heart rate variability modulation | Modulation of heart rate variability assessed through analysis of MSNA signal | 4 hours | |
Secondary | Non-invasive vagus nerve stimulation | Modulation of parasympathetic tone based on two different frequencies stimulation | 4hours | |
Secondary | Profile of response for MSNA | To describe positive and negative patterns of MSNA response | 4 hours |
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