Outcomes Following Pulmonary Valve Replacement in Adults

Heart Disease, Congenital Clinical Trial

Official title: Review of Outcomes Following Pulmonary Valve Replacement for Congenital Heart Disease in Adults

Status Completed

Clinical Trial Summary

One of the most common residual lesions in adult survivors of pediatric cardiac surgery is pulmonary valve disease, particularly regurgitation.

Multiple studies have demonstrated that placement of a pulmonary valve in such patients, results in improved ventricular function and resolution of symptoms. However, the optimal prosthetic valve for use in the pulmonary position has not been defined. There are essentially three alternatives available: the stented bioprosthetic valve, stentless bioprosthetic "tube" grafts used to replace the entire right ventricular outflow tract and mechanical valves.

All three of these valve options have been used in adults with congenital heart disease at Emory Healthcare and at Children's Healthcare of Atlanta at Egleston.

The goal of this study is to evaluate and compare the indications and short and mid-term outcomes for these alternative therapies.

Clinical Trial Description

n/a

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Heart Defects, Congenital
• Heart Disease, Congenital
• Heart Diseases
• Pulmonary Valve Replacement

• NCT number: NCT00276237
• Study type: Observational
• Source: Emory University
• Status: Completed
• Phase: N/A
• Start date: July 2005
• Completion date: November 2005