Heart Attack Clinical Trial
Official title:
Preventive and Personalized Medicine (2021-2023)
NCT number | NCT05090618 |
Other study ID # | 1187 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | October 23, 2021 |
Est. completion date | January 20, 2023 |
Verified date | March 2023 |
Source | Asfendiyarov Kazakh National Medical University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This is a GWAS study that aims to identify possible candidate genes associate to heart attack by exploring single nucleotide polymorphism (SNP) in a group of heart attack, in the Kazakh population. The investigators hypothesize that the careful phenotyping of the subject sand matching with increase the power to find SNP significantly associate with heart attack
Status | Completed |
Enrollment | 500 |
Est. completion date | January 20, 2023 |
Est. primary completion date | January 20, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 60 Years |
Eligibility | Inclusion Criteria: - Persons of Kazakh nationality - Age up to 59 years inclusive at the time of primary myocardial infarction - Myocardial infarction was established in accordance with the EOC criteria: An increase and / or decrease in the level of cardiac troponin must be combined with at least one of the following: • Symptoms of myocardial ischemia • Newly occurring ischemic changes on the ECG • The appearance of a pathological Q wave • Identification according to imaging data methods of new areas of non-viable myocardium, or new areas of local contractility disorders of presumably ischemic etiology • Detection of a thrombus in the coronary arteries according to coronary angiography - Presence of coronary angiography - Persons able and willing to provide written informed consent; Exclusion Criteria: - Age at primary myocardial infarction 60 years and older - Heart defects, congenital and acquired - Non-ischemic cardiomyopathies - Autoimmune diseases - Diabetes mellitus at the time of development of primary myocardial infarction - Terminal stages of renal and hepatic failure |
Country | Name | City | State |
---|---|---|---|
Kazakhstan | Kazakhstan | Almaty |
Lead Sponsor | Collaborator |
---|---|
Asfendiyarov Kazakh National Medical University |
Kazakhstan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | number of SNPs associated with Heart Attack | Using GWAS to identify candidate genes associate with Heart Attack | 1 year |
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