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Clinical Trial Summary

Obesity may directly or indirectly lead to hearing loss


Clinical Trial Description

Obesity is measured by Body Mass Index.it is calculated by dividing a person's weight in kilograms by the square of height in meters. For children and adolescent. Overweight is defined as Body Mass Index is <85th percentile <95th percentile but obesity is defined as body mass index at or above the 95th percentile for children and teens of the same age and sex the increasing in body mass index mass may affect auditory function Directly as adipose tissue secretes hormones and cytokines, proinflammatory cytokines lead to release of obesity-induced inflammation which may directly contribute to end-organ damage Also, Adiponectin, which is thought to have anti-inflammatory and antiatherogenic effects, and associated with favorable lipoprotein profile, independent of BMI and insulin resistance, low plasma concentrations of adiponectin have been associated with obesity in children. In adults, low level of adiponectin has been associated with elevated high-frequency thresholds.

Indirectly, by obesity comorbidities including Hypertension, Type 2 diabetes mellitus, Dyslipidemia , Metabolic Syndrome and Cardiovascular Diseases ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03172663
Study type Interventional
Source Assiut University
Contact mohammed salama bakr, Professor
Phone 1006550289
Email mohamedsalamabakr@yahoo.com
Status Not yet recruiting
Phase N/A
Start date May 1, 2018
Completion date November 1, 2019

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