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Hearing Loss clinical trials

View clinical trials related to Hearing Loss.

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NCT ID: NCT06268340 Not yet recruiting - Clinical trials for Hearing Loss, Sensorineural

Hearing and Structure Preservation Via ECochG

PRESERVE
Start date: February 29, 2024
Phase: N/A
Study type: Interventional

The goal of the study is to determine the benefit of using an ECochG-based corrective action guide during cochlear implant surgery compared to the traditional surgical approach without ECochG surveillance and guidance.

NCT ID: NCT06256081 Completed - Clinical trials for Hearing Loss, Conductive

Testing a New App for Children With Glue Ear

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

To assess whether children with glue ear ( and some normal hearing controls) and their families find the Hear Glue Ear application acceptable and easy to use. Whether the hearing screening section on the app is comparable to the hearing test data obtained from formal audiology hearing tests.

NCT ID: NCT06251817 Not yet recruiting - Normal Hearing Clinical Trials

The Wideband Acoustic Immittance Data in Thai Normal Hearing and Conductive Hearing Loss Adults

Start date: February 5, 2024
Phase:
Study type: Observational

The goal of this descriptive study is to collect the wideband immittance data in Thai normal hearing and conductive hearing loss adults. The main questions it aims to answer are: 1. What is normative data of wideband acoustic immittance in Thai normal hearing adults 2. What is the wideband acoustic immittance data in Thai conductive hearing loss who have type A, AS and Ad tympanogram Participants will examine hearing tests consequently - pure tone audiometry - Tympanometry with ipsilateral acoustic reflex - Wideband acoustic immittance

NCT ID: NCT06249919 Recruiting - Clinical trials for Sudden Sensorineural Hearing Loss

A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients

Start date: January 19, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The goal of this 2 step-up, exploratory study is to test safey, tolerability and PK/PD profiles in healthy volunteers and safety, tolerability and efficacy in sudden sensorineural hearing loss patients as an early salvage therapy. The main questions it aims to answer are: 1. whether is it safe and tolerable when healthy volunteers and sudden sensorineural hearing loss patients take multiple doses of NS101 against FAM19A5 2. whether is it effective in reversing hearing capability in sudden sensorineural hearing loss patients who fails to show sufficient recovery despite of oral standard steroid therapy. Patients and heathly volunteers will be given NS101 15mg/kg or 30mg/kg systemically less than 3 months per protocol. This is placebo controlled, double blinded study, which means there will be a group who receives placebo (i.e. fake drug) for study purpose.

NCT ID: NCT06249685 Completed - Hearing Loss Clinical Trials

Does Wearing Hearing Aids Impact the Affective State of Older Adults With Hearing Loss in Their Daily Lives?

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The proposed field trial will clarify the real-world effectiveness of HAs in remediating deficits in emotion processing for older adults with mild-to-moderate hearing loss. This study will employ a repeated reversal design to establish baseline affective state without HAs, when wearing amplification, and after HAs are removed. This study will triangulate self-report, behavioral, and physiological measures to capture nuances of emotional processing in the laboratory and in daily listening. Naturalistic stimuli will be used as it occurs in daily life to elicit emotional experiences, and ecological momentary assessment and commercially-available wearable sensors will be used to track changes in emotional state in daily listening. Anchoring real-world emotional experiences with controlled laboratory experiences will validate wearable sensors. Additionally, laboratory emotional stimuli will be related to real-world emotional experiences to establish the utility of laboratory stimuli in future studies. It is likely that benefits in emotional processing will have differential effects based on individual characteristics (such as degree of hearing loss, age, gender, cognitive ability, and personality), so participants will be analyzed according to larger groupings based on individual differences.

NCT ID: NCT06248398 Not yet recruiting - Clinical trials for Severe to Profound Hearing Loss

Impact of Robotic Cochlear Implantation on Hearing Performance in Noise

ROBOT-IC-BRUIT
Start date: February 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to compare two methods of cochlear implantation : conventional manual insertion versus robot-assisted in order to verify whether robotic insertion provides better performance in the noisy environment. To do this, we will compare the two methods of insertion of the electrode holder, on 140 patients candidates for cochlear implantation randomized in two groups (70 conventional surgery versus 70 robot-assisted surgery). All patients will be recruited during 17 months, in our Ear, nose and throat (ENT) Department of the Pitié-Salpêtrière hospital group, the first center for adult patients established in France (on average 180 patients/year). Patient will be followed for 9 months with clinical evaluation, imaging, audiometric, listening effort and quality of life assessments. These evaluations will be carried out preoperatively and postoperatively at 3 months and 6 months post-activation of the cochlear implant.

NCT ID: NCT06238102 Not yet recruiting - Hearing Loss Clinical Trials

Psychiatric and Cognitive Assessment of Adult Patients With Hearing Impairment

Start date: March 1, 2024
Phase:
Study type: Observational

1. Assess the impact of hearing impairment on cognition 2. Evaluate the impact of hearing impairment on mental health 3. Evaluate the impact of hearing impairment on quality of life 4. Assess the relation between hearing loss and psychiatric disorder

NCT ID: NCT06237790 Recruiting - Hearing Loss Clinical Trials

A Comparative Analysis of Speech Perception Between Cochlear Implant Patients and DFNB9 Patients Receiving Gene Therapy

Start date: April 6, 2024
Phase:
Study type: Observational

This cohort study aims to explore the trends and differences in multidimensional perceptual levels of patients after cochlear implants or gene therapy, as well as to comprehensively assess the efficacy of gene therapy for congenital deafness, thus providing a reference for making a well-rounded postoperative rehabilitation protocol for gene therapy patients.

NCT ID: NCT06235073 Completed - Clinical trials for Cochlear Hearing Loss

Robotic and Manual Cochlear Implantation: An Intra-individual Study of Speech Recognition and Electrode Holder Position (ICRobMan)

ICRobMan
Start date: July 1, 2023
Phase:
Study type: Observational

Cochlear implantation (CI) allows rehabilitation for patients with severe to profound hearing impairment. Although the use of a robotic assistant provides technical assistance to the surgeon, the assessment of the impact of its use on auditory outcomes remains uncertain, due to inter-individual variability of preoperative audiometric thresholds and the various possible intrascalar positions of the electrode array. WThe investigators aim to compare the hearing results of patients who underwent bilateral cochlear implantation, one side was performed with manual insertion and the other side with robot-assisted insertion. The electrode array intrascalar positioning and the surgery duration were also studied. This retrospective intra-individual study involved 10 patients who underwent bilateral cochlear implantation. The unique composition of this cohort enabled the investigators to utilize each patient as their own control.

NCT ID: NCT06229717 Not yet recruiting - Children, Only Clinical Trials

Vestibular and Postural Function in an Unselected Group of Children With Sensorineural Hearing Loss

VASIC
Start date: August 2025
Phase:
Study type: Observational

The goal of this prospective cohort study is to investigate the vestibular function in children with unilateral or bilateral sensorineural hearing loss. The main hypothesis of the study is that abnormal vestibular test results will be found in 20-30 % of the children with sensorineural hearing loss. The participants will be children in the age of 3-10 years with sensorineural hearing loss. The test protocol consists of questionnaires and vestibular and postural assessments.