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Hearing Loss clinical trials

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NCT ID: NCT05101083 Completed - Hearing Loss Clinical Trials

Speech Intelligibility in Quiet and Noise for New vs. Legacy Hearing Aids

Start date: October 25, 2021
Phase: N/A
Study type: Interventional

This clinical investigation is designed to compare audiological performance (i.e., measurements of sound quality and speech understanding) between Starkey's new receiver-in-canal device and a commercially available legacy receiver-in-canal device.

NCT ID: NCT05099146 Completed - Hearing Loss Clinical Trials

Impact of Oral Health Education on Oral Hygiene Status of Deaf Children

Start date: October 5, 2019
Phase: N/A
Study type: Interventional

Objective: To compare the impact of pictorial and video demonstration oral health educational interventions on oral hygiene status of children aged 12-16 years with hearing impairment. Methods: This randomized controlled trial spanned over the period of three months was conducted in purposively selected three schools of deaf children of Karachi. Baseline dental examination was performed to assess the dental plaque and gingival status of study participants. Dental plaque and gingival status of the participants was assessed by employing the World Health Organization recommended Plaque Index and Gingival Index. The 60 children were than randomly allocated into three interventional groups, pictorial, video and control, 20 in each group. The children were examined again after one month of oral health education provision by single examiner. Tooth brushes were provided to students at the time of baseline examination to use for one month. Collected data was subjected to statistical analysis and described in terms of Mean and Standard Deviation, mixed model ANNOVA was applied to see the difference between the mean plaque and gingival scores of three groups after one month. The p-value of <0.05 was considered as statistically significant at the 95% confidence interval.

NCT ID: NCT05086809 Completed - Hearing Loss Clinical Trials

Investigation of an Updated Bone-anchored Sound Processor

Start date: September 30, 2021
Phase: N/A
Study type: Interventional

The study is a prospective, single-center, comparative, cross-over study with within-subject control design. In the investigation an updated sound processor will be tested at compared to the CE marked Ponto 3 SuperPower sound processor (available on the market since December 2016) in order to establish marketing claim(s) on the updated sound processor. The performance of the two sound processors will be evaluated via speech and hearing tests, and patient reported outcomes.

NCT ID: NCT05086276 Completed - Clinical trials for Hearing Loss, Sensorineural

FX-322 in Adults With Acquired Sensorineural Hearing Loss

Start date: October 12, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase 2, prospective, randomized, double-blind, placebo-controlled, single-dose, multicenter study to evaluate the efficacy of FX-322, administered by intratympanic injection, in adults with acquired sensorineural hearing loss (SNHL).

NCT ID: NCT05083221 Recruiting - Older Adults Clinical Trials

Effect of an Aural Rehabilitation Program in Hearing-impaired Older Adults

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Hearing impairment in older adults is becoming a common health problem as the population ages. The impact of hearing impairment in older adults includes not only physical function and cognitive performance, but also depression, loneliness and social isolation, as well as having a negative impact on quality of life and financial status. Therefore, an audiological rehabilitation program intervention is recommended. The purposes of this study are to examine the effects of an audiological rehabilitation program (Hear-Talk-Activity audiological rehabilitation program) intervention on communication abilities, depression, loneliness and quality of life outcomes in older adults with hearing impairment. The single-blind, randomized control trial will include older adults aged 65 years or older with hearing impairment and aid user. Participants will be randomized to either intervention groups or control groups.

NCT ID: NCT05079867 Recruiting - Hearing Loss Clinical Trials

Cochlear Trauma, Functional and Structural Preservation in Cochlear Implant Surgery

Start date: July 19, 2021
Phase:
Study type: Observational

Prospective 2-arm cohort consisting of a preoperative visit and visits at the time of implantation (Day 0) and follow-up in patients for whom their treating physician indicated a perimodiolar or straight cochlear implant.

NCT ID: NCT05076344 Recruiting - Hearing Loss Clinical Trials

Understanding the Consequences of Recreational Noise Exposure

Start date: May 19, 2022
Phase:
Study type: Observational

The aim of this study is to determine whether measures derived from Magnetic Resonance Imaging (MRI) scans, and clinical and behavioural measures of hearing loss, in the peripheral and central auditory system (ranging from the cochlear nerve through the auditory brainstem to the auditory cortex) are associated with age and history of noise exposure in otherwise healthy adult humans.

NCT ID: NCT05076045 Completed - Clinical trials for Hearing Loss, Age-Related

Effects of PSAPs on Speech Processing

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Mild to moderate hearing loss remains undertreated, largely because of the high cost of hearing aids. A promising and much less expensive alternative is the use of personal sound amplification products (PSAPs), which are electronic, portable, over-the-counter devices that amplify sound. Studies have shown that the use of PSAPs provides significant hearing benefits and improves the quality of life for older adults with mild to moderate hearing loss. However, there is insufficient data to determine the impact of PSAPs use on speech processing in the brain. The purpose of this study is to use electroencephalography (EEG) measurements to assess the neurobiological and behavioral effects of PSAPs on speech perception in noise in individuals with mild to moderate hearing loss. The investigators expect that the PSAPs use will result in an immediate improvement in the ability to perceive speech-in-noise, supporting that these hearing devices may be a means of restoring communication skills in people with mild to moderate hearing loss. Behavioral benefits will be associated with increased brain activity in auditory regions and connectivity between auditory and speech regions in the brain.

NCT ID: NCT05073796 Completed - Deafness, Bilateral Clinical Trials

Cochlear Implant Electrostimulation and the Influence on the Vestibular Organ

Start date: September 9, 2020
Phase: N/A
Study type: Interventional

There is evidence that the sensor function of the utricle in patients with bilateral labyrinthine dysfunction (bilateral vestibulopathy) may improve balance under the influence of high frequency basal stimulation of the cochlea. The aim of the study is to measure the possible co-stimulation of the utricle (which is determined by the SVV) by tonotopic (frequency-specific) cochlear stimulation and thus to objectify whether the stimulation of the auditory nerve in CI patients also leads to an unavoidable co-stimulation of the vestibular system.

NCT ID: NCT05072470 Completed - Hearing Loss Clinical Trials

Benefits of Assistive Listening Device for Speech Intelligibility

Start date: October 18, 2021
Phase: N/A
Study type: Interventional

Speech intelligibility in noise will be evaluated in adults with moderate to moderate-severe sensorineural hearing loss, using an assistive listening device and hearing aid, and compared to speech intelligibility in noise using hearing aids alone.