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Hearing Loss clinical trials

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NCT ID: NCT05854719 Recruiting - Hearing Impairment Clinical Trials

Eyes On Lips? Speechreading Skills and Facial Expression Discrimination in Children With and Without Impaired Hearing

Start date: May 12, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to find out the role of background factors and gaze use in children's speechreading performance. The main questions it aims to answer are: - Which background factors and eye gaze patterns are associated with the best speechreading results in hearing children and those with hearing impairment/loss? - Are children's gaze patterns and facial expression discrimination associated with interpretation of emotional contents of verbal messages in speechreading? - What is the efficacy of intervention that is based on the use of a speechreading application to be developed? Participants will be - tested with linguistic and cognitive tests and tasks - tested with a speechreading test and tasks with or without simultaneous eye-tracking - about half of the participants with hearing impairment/loss will train speechreading with an application Researchers will compare the different age groups and the results of hearing children to those of children with impaired hearing to see if there are differences.

NCT ID: NCT05849519 Recruiting - Clinical trials for Sudden Sensorineural Hearing Loss

Small Sample,Unicentric,Randomized, Controlled Clinical Study of Coenzyme I for Injection in the Treatment of Sudden Sensorineural Hearing Loss

Start date: February 16, 2022
Phase: Early Phase 1
Study type: Interventional

Sudden sensorineural hearing loss is one of the most common emergencies in otorhinolaryngology, and its incidence is increasing year by year and tends to be younger. At present, the pathogenesis of sudden deafness is not clear and the individual treatment effects vary significantly. In order to break through this specific treatment bottleneck, this project pioneered the clinical application of the co-regulator nicotinamide adenine dinucleotide (NAD+) in the treatment of sudden deafness. Therefore, this project intends to use pure tone audiometry, speech audiometry, tinnitus disability scale THI, tinnitus subjective visual analog score method VAS, ear fullness subjective visual analog score method VAS for data analysis, and explore the safety of coenzyme I for injection on sudden deafness and efficacy assessment.

NCT ID: NCT05848661 Not yet recruiting - Clinical trials for Hearing Loss, Age-Related

Evaluation of a Digital Therapy of Auditory Training

AUDISSEE
Start date: September 2024
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the efficiency of the medical device AUDISSEE in improving the perception in noise ability of presbycusis patients with hearing-aids.

NCT ID: NCT05847556 Recruiting - Hearing Loss Clinical Trials

Video Game Hearing Tests for Remote Monitoring of Ototoxicity

VAROT
Start date: March 16, 2022
Phase: N/A
Study type: Interventional

The reason for this clinical trial is to test different ways of carrying out hearing tests to be able to detect for hearing loss within the hospital and at home. Pathway 1: The goal of this clinical trial is to learn whether video game hearing tests work well to detect hearing loss caused by antibiotics at home in patients with long-term lung infections. Pathway 2: The goal of this clinical trial is to compare tablet-based (iPad) hearing tests with formal sound booth hearing tests in patients attending hospital outpatient clinics. Pathway 3: The goal of this clinical trial is to learn whether audio-training improves listening to speech in the presence of background noise. Researchers will compare participants receiving audio-training with those who did not receive audio-training. This will test if audio-training can improve participant's everyday listening experiences.

NCT ID: NCT05847426 Recruiting - Hearing Impairment Clinical Trials

Improving Early Intervention in Hearing Impaired Children Using Functional Near-Infrared Spectroscopy (fNIRS)

Start date: May 2, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to find out whether hearing test results using functional near-infrared spectroscopy (fNIRS) will help to fast-track early intervention for infants born with a hearing loss. fNIRS is a method of imaging brain activity using light. The main questions are: 1. Can audiologists make more confident decisions about the optimal interventions at different critical points in the hearing care pathway when they are given additional fNIRS information compared to when they have standard audiology test results alone? 2. Is the experience of their infant having an fNIRS test acceptable and comfortable for the parents or care givers?

NCT ID: NCT05837728 Recruiting - Frailty Clinical Trials

Health Determinants in Older Adults Living at Home

Start date: March 1, 2023
Phase:
Study type: Observational

The observational study will conduct interprofessional assessments by registered nurses, physiotherapists, and occupational therapists of health determinants (i.e., frailty, physical, cognitive, and sensory function, mental and social health, and alcohol use) in older adults (≥75) living at home and applying for a municipal health service. The participants will take part in two assessments, baseline and 5 months. Based on the baseline assessment healthcare professionals will identify factors that can affect older adults' health, provide tailored information, offer measures, and link with proper health services. The aim is that older adults maintain health, function, and self-care and thus can continue aging at home. The main research question is:) How can interprofessional assessments of older adults living at home reduce the risk of impaired function, maintain health and ensure that the elderly receive tailored services?

NCT ID: NCT05828017 Completed - Clinical trials for Hearing Loss, Sensorineural

Investigating Hearing Aid Frequency Response Curves 2

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

Internal research on the manufacturer's hearing aid products has idenitfied areas in which the investigators can improve the hearing aid frequency response curve. Based on the conclusions of the first study, we have identified areas that require further analysis and testing prior to implementing of the proposed frequency response curve into our products. This study aims to investigate the current freqeuncy response curve in the manufacturer's products to variations of these curves to determine if hearing aid users prefer the variations over the manufacturer's standard curve.

NCT ID: NCT05821959 Recruiting - Clinical trials for Sensorineural Hearing Loss, Bilateral

Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss

Start date: September 15, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Part A of this trial will evaluate the safety and tolerability of a single unilateral administration of one of two dose levels of AAVAnc80-hOTOF and will evaluate the Akouos delivery device to safely achieve the intended product performance.

NCT ID: NCT05815667 Active, not recruiting - Hearing Impairment Clinical Trials

Effects of the Swedish Internet-based Individualised Active Communication Education (I-ACE) in FTU

I-ACE
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Hearing impairment affects the ability to communicate, which can adversely affect both mental and physical health. The most common used rehabilitation method in hearing impairment is hearing aid fitting. Even with optimally fitted hearing aids, many struggle to hear in situations with difficult listening conditions. Active Communication Education (ACE) is an interactive group rehabilitation programme aiming to help those with hearing loss communicate more effectively using communication strategies to cope better in everyday life. An Individualised Active Communication Education (I-ACE) distributed digitally could enable those unable to get to the hearing care facility, or don't want to join the group sessions to benefit from the programme. This project aims to investigate the effects of the swedish digital version of the I-ACE in first time hearing aid users.

NCT ID: NCT05808543 Not yet recruiting - Hearing Loss Clinical Trials

BEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear Implants

BEARS
Start date: April 2023
Phase: N/A
Study type: Interventional

The goal of the BEARS clinical trial is to determine whether using the directional listening training delivered via the BEARS training package for 3-months alongside usual care compared to only receiving usual care improves speech-in-noise perception, hearing experiences, vocabulary and quality of life and reduces listening effort in young people between 8-16 years old (inclusive) with two cochlear implants. The participants will complete hearing assessments and questionnaires before completing the 3-month intervention. They will be followed up for the next 9-months through online and in-person appointments.