Application of Ideal Binary Masking to Disordered Speech

Hearing Loss, Sensorineural Clinical Trial

Official title:

Application of Ideal Binary Masking to Disordered Speech

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05244603
• Other study ID #: 10710
• Status: Completed
• Phase: Early Phase 1
• Start date: December 1, 2021
• Est. completion date: December 30, 2023

Study information

• Verified date: April 2024
• Source: Utah State University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Dysarthria and hearing loss are communication disorders that can substantially reduce intelligibility of speech and the addition of background noise adds a further challenge. This proposal utilizes an established signal processing technique, currently exploited for improved understanding of speech in noise for listeners with hearing loss, to investigate its potential application to overcome speech-in-noise difficulties for listeners understanding dysarthric speech. Successful completion of this project will demonstrate proof-of-concept for the application of this signal processing technique to dysarthric speech in noise, and inform the development of an R01 proposal to perform a large-scale evaluation of the technology, and clinically meaningful implications, in a broad range of disordered speech types and severities.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 447
• Est. completion date: December 30, 2023
• Est. primary completion date: December 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:INCLUSION CRITERIA for All Participants

• Native speakers of American English
• No history of speech or language impairment
• No significant prior contact with persons having neurogenic speech disorders INCLUSION CRITERIA for Participants with Normal Hearing
• 18 to 70 years of age
• Auditory thresholds of 20 dB HL or better bilaterally at octave frequencies from 250-8000 Hz (if under 55 years of age)
• Auditory thresholds of 25 dB HL or better bilaterally at octave frequencies from 250-4000 Hz (if over 55 years of age) INCLUSION CRITERIA for Participants with Sensorineural Hearing Loss
• 18 to 90 years of age

Exclusion Criteria:

• EXCLUSION CRITERIA for All Participants
• Mild or profound hearing loss
• Conductive or mixed hearing loss
• Asymmetric hearing loss
• Obvious concomitant cognitive or mental impairment
• Unable to achieve upward of 20% words correct

Related Conditions & MeSH terms

• Dysarthria
• Hearing Loss
• Hearing Loss, Sensorineural

Intervention

Behavioral:
• Ideal binary mask
Speech in noise processed by ideal binary mask to reduce background noise

Locations

Country	Name	City	State
United States	Utah State University	Logan	Utah

Sponsors (1)

Lead Sponsor	Collaborator
Utah State University

Country where clinical trial is conducted

United States, 

References & Publications (1)

Borrie SA, Yoho SE, Healy EW, Barrett TS. The Application of Time-Frequency Masking To Improve Intelligibility of Dysarthric Speech in Background Noise. J Speech Lang Hear Res. 2023 May 9;66(5):1853-1866. doi: 10.1044/2023_JSLHR-22-00558. Epub 2023 Mar 21 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percent correct speech intelligibility	Percent of keywords correctly identified by the participant for the unprocessed and processed speech stimuli	One hour