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Hearing Loss, Sensorineural clinical trials

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NCT ID: NCT03718975 Completed - Hearing Loss Clinical Trials

Quality Control of CE-Certified Phonak Hearing Aids - 2018_28

Start date: September 10, 2018
Phase: N/A
Study type: Interventional

Phonak Hearing Systems pass through different development and study stages. At an early stage, feasibility studies are conducted to investigate new algorithms, features and functions in an isolated manner. If the benefit is proven, their performance is then investigated regarding interdependency between all available algorithms, features and functions running in parallel in a hearing aid (pivotal/pre-validation studies) and, as a result, they get optimized. Afterwards, and prior to product launch, the Phonak Hearing Systems undergo a final quality control in terms of clinical trials. This is a pre-validation study, investigating optimized algorithms, features, functions and wearing comfort. This will be a clinical investigation which will be conducted mono centric at Sonova AG Headquarters based in Stäfa (Switzerland).

NCT ID: NCT03674086 Completed - Clinical trials for Hearing Loss, Sensorineural

Evaluation of the eAdjust Application

Start date: August 23, 2018
Phase:
Study type: Observational

Despite being effective, the majority of people who would benefit from using hearing aids do not access them. For those who do obtain hearing aids, around 20% do not wear them regularly. People often do not use their hearing aids because they continue to experience difficulties when listening to and understanding speech in noisy situations. Conventional hearing aids must be programmed and adjusted by a trained audiologist with specialist equipment and therefore provide limited user-control over the hearing aid's functionality. In comparison to conventional hearing aids, Smartphone-connected hearing aids enable patients to adjust their programmes themselves in different situations using a Smartphone application. Smartphone-connectivity can supplement clinical practices, as patients can adjust their hearing aids without the need to visit the clinic. This has the potential to empower patients to be actively involved in their own hearing healthcare. A systematic review assessing the effectiveness of alternative listening devices showed that there is no published high-quality research assessing the clinical effectiveness of Smartphone-connected hearing aids. Furthermore, a usability research study has shown that patients want to personalise and adjust their own HA programmes to meet their individual needs. Having carried out the early development work, the next step would be to carry out a study to evaluate smartphone-connected hearing aids, in accordance with the MRC guidelines on developing and evaluating complex interventions. This study will assess the benefits of a smartphone application, eAdjust that has been developed for use with Phonak Audeo B90-Direct hearing aids. The eAdjust app connects to the hearing aid via Bluetooth, and enables hearing aid users to fine-tune their hearing aids via their smartphone. The benefits of the eAdjust app will be assessed in the real-world as well as in the laboratory. A mixed methods approach will be taken, using both behavioural and patient reported outcomes.

NCT ID: NCT03616223 Completed - Clinical trials for Sensorineural Hearing Loss

FX-322 in Sensorineural Hearing Loss

Start date: July 3, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase 1/2 study of FX-322 at two dose levels compared to placebo in male and female adults otherwise healthy with stable sensorineural hearing loss.

NCT ID: NCT03613909 Completed - Clinical trials for Hearing Loss, Sensorineural

Acceptance of the CP950 Sound Processor

Start date: November 2015
Phase: N/A
Study type: Interventional

Acceptance of CP950 sound processor with experienced CP810/CP910/CP920 BTE sound processor users.

NCT ID: NCT03603314 Completed - Clinical trials for Severe Sudden Sensorineural Hearing Loss

Efficacy of SENS 401 in Subjects With Severe or Profound Sudden Sensorineural Hearing Loss

AUDIBLE-S
Start date: February 15, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Primary objective of the study is to assess the efficacy of SENS-401 on hearing loss in comparison to placebo at the end of the 4-week treatment period

NCT ID: NCT03582566 Completed - Clinical trials for Hearing Loss, Sensorineural

Training Language and Literacy for Children Who Use CIs

Start date: July 1, 2016
Phase: N/A
Study type: Interventional

This study aims to determine the effectiveness of computer games to improve language and literacy outcomes for children who have hearing loss. Children will be assigned to one of four conditions: phonological awareness training, working memory training, phonological awareness + working memory training, or active control.

NCT ID: NCT03555084 Completed - Clinical trials for Hearing Loss, Sensorineural

Quality Control of CE-Certified Phonak Hearing Aids - 2018_07

Start date: May 22, 2018
Phase: N/A
Study type: Interventional

Phonak Hearing Systems pass through different development and study stages. At an early stage, feasibility studies are conducted to investigate new algorithms, features and functions in an isolated manner. If the benefit is proven, their performance is then investigated regarding interdependency between all available algorithms, features and functions running in parallel in a hearing aid (pivotal/pre-validation studies) and, as a result, they get optimized. Afterwards, and prior to product launch, the Phonak Hearing Systems undergo a final quality control in terms of clinical trials. This is a pre-validation study, investigating optimized algorithms, features, functions and wearing comfort. This will be a clinical evaluation which will be conducted mono centric at Sonova AG Headquarters based in Stäfa (Switzerland).

NCT ID: NCT03512951 Completed - Clinical trials for Hearing Loss, Sensorineural

Subjective Evaluation of a Sound Processing Method for Hearing Aids on Auditory Distance Perception

EXTEND
Start date: October 9, 2018
Phase: N/A
Study type: Interventional

Within the course of this study, a signal processing feature has been developed at Ecole Polytechnique Fédérale de Lausanne (EPFL), in collaboration with Sonova AG, in order to enhance the listening experience with remote microphone systems. In particular, the developed feature is supposed to improve the so-called audio-visual fusion, i.e. the fact to perceive the sound as coming from the physical location of the source. One of the main goals of the present study is to evaluate the extent to which this feature reaches that objective.

NCT ID: NCT03509974 Completed - Clinical trials for Unilateral Mixed Conductive and Sensorineural Hearing Loss (Diagnosis)

Early Experience of a New Implant System for Bone Conduction Hearing in the Pediatric Population

OSIA Pediatric
Start date: April 18, 2018
Phase: N/A
Study type: Interventional

To study the initial experience with implanting and fitting a new Bone Conduction system in pediatric patient population with conductive, mixed or single-sided deafness.

NCT ID: NCT03500718 Completed - Clinical trials for Cochlear Hearing Loss

Changes in the Threshold of Electrically Evoked Compound Action Potential in Children Following Cochlear Implantation

Start date: February 26, 2018
Phase: N/A
Study type: Interventional

After cochlear implantation, cochlear nerve is stimulated by giving a current over the electrodes placed in the cochlea and the current is measured by electrically evoked Compound Action Potential (ECAP).This ECAP is measured intra operatively, after 4 weeks( at switch on), after 3months and 6 months following cochlear implantation.