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Hearing Loss, Sensorineural clinical trials

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NCT ID: NCT05180630 Completed - Clinical trials for Hearing Loss, Sensorineural

Sound Quality Comparisons With Different Hearing Aid Couplings and Venting Systems

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Participants will be comparing the sound quality of their own voice and the sound quality of streamed music using universal couplings and a custom earmold with a dynamic vent.

NCT ID: NCT05112354 Completed - Clinical trials for Idiopathic Sudden SNHL

Predictive Factors for Recovery in Idiopathic Sensory Neural Hearing Loss

Start date: December 1, 2019
Phase: Phase 2
Study type: Interventional

Sudden sensorineural hearing loss (SSNHL) is an otological emergency that is defined as a hearing loss greater than 30 dB over three consecutive frequencies within 72 hours, with abnormalities of the cochlea, auditory nerve, or central auditory system.1 During 2006 and 2007, the annual incidence of SSNHL was 5-27/100,000 persons per year in the United states.2,3 The causative etiologies for SSNHL included viruses, microcirculation abnormalities, and autoimmune disorders. However, definitive evidence remains elusive.4,5 Currently, steroids are the treatment of choice due to their effects on the inner ear such as immunosuppression and circular enhancement.6,7 Combined systemic and intra-tympanic steroid treatment has previously been reported to be beneficial for SSNHL patients, with overall better treatment outcomes.8,9 However, due to the heterogeneous pathological nature and spontaneous recovery potential of the disease, few controlled studies exist in the literature. As a result, the treatment strategies of SSNHL remain a controversial issue in clinicalpractice .10 The condition exhibits a wide age distribution , with an average of 50-60 years and no sex preference. The hearing loss is unilateral in most Population studies of sudden sensorineural hearing loss cases, with bilateral involvement reported in less than 5%. 11 The severity of the hearing loss is divided roughly equally into mild, moderate, and severe profound. The configuration of the hearing loss varies and can affect high, low, or all frequencies. Tinnitus occurs in about 80% of patients, and vertigo, indicating an associated peripheral vestibular dysfunction, in about 30%. 12 The response to medical therapy shows inconsistent results regarding symptoms especially hearing loss may be due to the uncertainty about the cause of the disease and its progress. little is known about the factors which may contribute to either success or failure of the medical therapy. Aim of work 1. To evaluate the factors contributing to the success or failure of standardized medical therapy in cases of ISSNHL 2. To detect the degree of correlation of the presenting symptoms and comorbidities to the patient final hearing prognosis.

NCT ID: NCT05101083 Completed - Hearing Loss Clinical Trials

Speech Intelligibility in Quiet and Noise for New vs. Legacy Hearing Aids

Start date: October 25, 2021
Phase: N/A
Study type: Interventional

This clinical investigation is designed to compare audiological performance (i.e., measurements of sound quality and speech understanding) between Starkey's new receiver-in-canal device and a commercially available legacy receiver-in-canal device.

NCT ID: NCT05086276 Completed - Clinical trials for Hearing Loss, Sensorineural

FX-322 in Adults With Acquired Sensorineural Hearing Loss

Start date: October 12, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase 2, prospective, randomized, double-blind, placebo-controlled, single-dose, multicenter study to evaluate the efficacy of FX-322, administered by intratympanic injection, in adults with acquired sensorineural hearing loss (SNHL).

NCT ID: NCT05072457 Completed - Clinical trials for Hearing Loss, Sensorineural

Benefit of Assistive Listening Device for Lateralization

Start date: October 18, 2021
Phase: N/A
Study type: Interventional

Speech intelligibility in noise will be evaluated in adults with moderate to moderate-severe sensorineural hearing loss using a Phonak Roger microphone and hearing aid with compatible Phonak Roger receiver. Target speech will be presented from multiple directions while competing diffuse background noise is presented simultaneously. Participants will repeat back words and percent correct is calculated.

NCT ID: NCT05052944 Completed - Hearing Loss Clinical Trials

Single-sided Deafness and Cochlear Implantation

Start date: November 19, 2020
Phase:
Study type: Observational [Patient Registry]

This observational study evaluates the effects of cochlear implantation in patients with deafness in one ear.

NCT ID: NCT04987021 Completed - Clinical trials for Hearing Loss, Sensorineural

An Actual Use, Open-label Study Assessing Usability of Remote Assist to Program Cochlear Implant Recipients

RAL
Start date: August 27, 2021
Phase: N/A
Study type: Interventional

Clinical management of cochlear implant (CI) recipients involve programming, counselling, performance evaluation and habilitation. This requires the recipients to travel to the clinic for follow up appointments which can pose significant challenges for recipients, particularly those who live far away from the clinic. Remote Assist (RA) is a new solution that allows the clinician to make MAP and sound processor adjustments via the recipient's Nucleus Smart app (NSA) installed on their smart phone. With RA the clinician can also perform counselling using a video call directly via the NSA. As RA uses no specialized hardware and software that needs to be sent and retrieved back from the recipient, it has the potential to further improve the remote programming experience and convenience for both the recipient and the clinician.

NCT ID: NCT04922619 Completed - Clinical trials for Sensorineural Hearing Loss, Bilateral

Study of Music and Speech Perception in New Cochlear Implanted Subjects Using or Not a Tonotopy Based Fitting

Start date: June 10, 2021
Phase: N/A
Study type: Interventional

Main objective: Show the superiority of tonotopy based fitting strategy compared to default fitting strategy on the perception speech in noise. Secondary objectives: Show the superiority of tonotopy based fitting strategy compared to default fitting strategy on the perception of musical elements (contour test). Show the non inferiority of tonotopy based fitting strategy compared to default fitting strategy on the perception of speech elements in quiet. Show the superiority of tonotopy based fitting strategy compared to default fitting strategy on the qualitative preference for the listening of musical pieces.

NCT ID: NCT04839289 Completed - Clinical trials for Hearing Loss, Sensorineural

Hearing Aid Signal Processing Comparative Study

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

Participants will be fit with each of two hearing instruments in an ABA cross-over design. The study will consist of a total of three approximately 10-day home trials with the devices. Participants will be asked to provide qualitative feedback to investigators regarding the performance of and their preference for each hearing instrument.

NCT ID: NCT04823494 Completed - Clinical trials for Hearing Loss, Sensorineural

Wear-Time Trial for Self-Fitting Hearing Aid

Start date: June 18, 2021
Phase: N/A
Study type: Interventional

This document describes a clinical validation study for a double-blind repeated-measures comparative study of the Great Nordic (GN) self-fitting method to a validated audiology-best-practices method when fitting the GN Self-fitting Hearing Aid, a device intended for persons aged 18-75 years old who have mild-to-moderate hearing loss. A crossover wear-time field trial will be conducted. The focus of the study is on the validity of the self-fitting process used to select appropriate frequency-gain characteristics for the GN Self-fitting Hearing Aid, and the safety and effectiveness of the device.