View clinical trials related to Hearing Loss, Cochlear.
Filter by:This study is to build a cohort of sudden sensorineural hearing loss (SSNHL) patients. When the patient visited the Department of otolaryngology clinic for hearing loss, we can diagnose the SSNHL following the result of pure tone audiometry and the history of the patient. The cohort is a system that tracks the hearing recovery status, timing, and degree of recovery of patients who received cocktail therapy with or without high-dose steroids, vasodilators, antiviral agents, and intratympanic steroid injections, satellite ganglion block, and hyperbaric oxygen therapy.
Hearing-aid (HA) users with insufficient HA may be better helped with a "Bimodal solution" when replacing the HA with a Cochlear implant (CI) to the poorer hearing ear and a HA to the better hearing ear. This randomised controlled trial can show the benefit in terms of better speech perception of the bimodal solution with CI to the poorest hearing ear compared to binaural hearing aids. It can clarify if HAs users with insufficient HAs benefit will benefit from the bimodal solution when adding a CI to the poorer hearing ear in terms of better speech perception. It can report the degree of perceived hearing handicap in bimodal CI-users versus bilateral HA-users by hearing -specific patient reported outcome measures (PROM) questionnaires. And it can contribute to a specific cochlear implant candidacy criterion related to the transition from HA treatment to the CI treatment. The purpose of this study is to determine if bimodal treatment with a hearing aid to the better hearing ear and CI to the poorer hearing ear increases the ability to understand speech and improve quality of life compared to patients that are treated with hearing aids only. The benefit of bimodal fittings compared to the best possible bilateral HA treatment will be evaluated.
In France, children cochlear implantation (CI) is performed 400 times per year. Causes of profound sensorineural hearing loss (SNHL) are represented by congenital malformation of the inner ear for 50 to 60%. Most of the remaining cases of CI in children are caused by congenital CMV infection. The proportion of CMV inducing SNHL with a CI in children is not clearly defined. During CI, we aim to collect a very small sample of perilymphatic fluid and to analyse it with a CMV polymerised-chain-reaction to evaluate the involvement of CMV in SNHL.
Sixty (60) subjects between the ages of 7 months and 5 years, 11 months will be implanted with the MED-EL SYNCHRONY/SYNCHRONY 2 Cochlear Implant System. All subjects will demonstrate a severe to profound sensorineural hearing loss (SNHL) in the high frequencies (2000 Hz and above) and insufficient functional access to sound with appropriately fit amplification and aural habilitation. Additionally, subjects implanted under 12 months of age will demonstrate a severe to profound sensorineural hearing loss, defined by a 3-frequency Pure Tone Average (PTA) of ≥ 70 dB HL at 500, 1000 and 2000 Hz, while subjects 12 months to 5 years, 11 months of age will demonstrate a mild to profound sensorineural hearing loss in the low frequencies, defined by a 3-frequency PTA of ≥ 25 dB HL at 500, 1000 and 2000 Hz. For the purposes of this study, insufficient functional access to sound for children who lack the requisite language to complete open-set word recognition testing will be based on the LittlEARS Auditory Questionnaire (LEAQ) and defined as a Total Score below the expected value for normal hearing (NH) children of the same chronological age1. For children with the requisite language to complete MLNT/LNT testing, insufficient functional access to sound will be defined by word recognition scores of ≤ 60% on the MLNT/LNT. Subjects will be followed for twelve (12) months following initial activation of the audio processor, with post-operative evaluations occurring at device.
This trial is a pilot study to assess the feasibility of using Electrocochleography recorded from a cochlear implant intra-operatively in real time to monitor the progress of its insertion. Correlation between: 1. Observed changes in this signal during surgery and residual hearing loss post-operatively and 2. Recordings of this signal post-operatively and actual pure tone audiometry results will also be assessed.