Hearing Impairment Clinical Trial
Official title:
Prevalence and Associations of Paediatric Chronic Suppurative Otitis Media and Hearing Impairment in a Rural District of Malawi: A Cross-sectional Survey
This community-based cross-sectional survey will estimate the frequency and risk factors of Chronic Suppurative Otitis Media and Hearing Impairment in Children ages 4-6 years in the Chikwawa District. These data will be useful for service planning, disease prevention efforts and to guide future research in this field.
Type of research study:
Cross sectional survey
Problem to be studied:
Chronic suppurative otitis media and hearing impairment are important causes of morbidity,
affecting 4-10% of children throughout sub-Saharan Africa. Many of the causes of disease are
preventable with simple interventions. There is significant variation in disease burden and
causes between countries, and currently no data on the frequency and causes of disease in
Malawi.
Previous studies suggest poverty, crowding, paternal smoking and indoor cooking all increase
the risk of developing chronic suppurative otitis media. The associations with use of an
efficient cookstove have not been studied. The causes of childhood hearing impairment vary
significantly by region and include otitis, other infections and cryptogenic causes.
Objectives:
- Estimate the prevalence of CSOM and other ear pathology in a population representative
sample of 4-6 year-old children in a rural district of Malawi.
- Describe associations (including household use of an efficient cookstove) of CSOM
- Estimate the prevalence of hearing impairment defined by screening audiometry in a
population representative sample of 4-6 year-old children in a rural district of
Malawi.
- Describe associations of hearing impairment in a population representative sample of
4-6 year-old children in a rural district of Malawi.
Methodology:
A village level cluster survey in the Chikwawa district of Malawi. The study will survey 270
children across 10 systematically determined clusters using 2008 census data. The
investigators will undertake video otoscopy and basic hearing screening in the field using a
validated smartphone screening tool. The research will also look for associations between
chronic middle ear infection and potential risk factors for disease using negative binomial
regression. This will include household use of an efficient cookstove.
Expected findings and their dissemination:
The investigators will establish the prevalence and associations of chronic suppurative
otitis media and of hearing impairment in children aged 4-6 years in the Chikwawa district.
The investigators hope these data will guide further development of ENT service in Malawi,
and may indicate possible preventative strategies. The results will be disseminated to the
communities, local health services and the College of Medicine of Malawi.
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Observational Model: Case-Only, Time Perspective: Prospective
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