Healthy Young Men Clinical Trial
Official title:
Effects of Aronia Berry (Chokeberry) Extract on Vascular Function in Healthy Men: a 3 Month Randomized Controlled Trial.
There is an increasing interest in the effects of various food derived polyphenols on
vascular function. Arguably the most well-established vascular benefits are attributed to
flavanols from cocoa beans and this has been supported by a successful health claim through
the European Food Safely Authority in 2012. Berry fruits are another rich source of
polyphenols that have vasoactive properties, and there is a growing body of research
exploring these effects in various berries (blueberries, cranberries, strawberries) and other
fruit products with similar polyphenol composition. A key (poly)phenol in berries and other
fruits believed to provide much of the benefit is anthocyanins. When given as an isolated
extract, 320 mg anthocyanins have been found to improve blood vessel function both acutely
and in response to chronic consumption over 12 weeks.
Aronia berries are a native North American berry with high naturally occurring anthocyanins
among other polyphenols. Based on their polyphenol composition, there is growing interest in
the potential for Aronia berries to elicit health promoting cardio-metabolic effects.
Specifically, Aronia berry extracts, which provide a concentrated source of polyphenols, may
improve blood vessel function.
Thus, the primary focus of this project is to evaluate the effects of Aronia berry extracts
of differing polyphenol dose on vascular endothelial function.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05306366 -
A Brain Imaging PET Study of [11C]-Lu AF90103 in Healthy Adult Male Participants
|
Phase 1 | |
| Recruiting |
NCT05718752 -
Characterization of the Plasma Metallomic Profile to Acute Exercise in Healthy Men and Women (METALEXO)
|
||
| Completed |
NCT01812967 -
Mechanism of Action of Milk and Its Components on Glycemic Control in Healthy Young Men
|
N/A |