Healthy Volunteers Clinical Trial
Official title:
ChronoMet: Metabolic and Inflammatory Effects of Eating Timing and Quantity
Verified date | June 2024 |
Source | University of Minnesota |
Contact | Lesia Lysne |
Phone | 612-301-7040 |
endores[@]umn.edu | |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This is an observational study to address the important knowledge gap of the metabolic and inflammatory impact of acute overeating and whether timing of acute overeating may modify these effects. The hypothesis is that acute overconsumption of calories will promote inflammation and metabolic dysfunction, with the most detrimental effects observed with evening caloric overconsumption. The expectation is that this study to provide critical insights into the biological consequences of overeating, which will direct novel approaches combating overeating and its detrimental health effects.
Status | Recruiting |
Enrollment | 60 |
Est. completion date | February 15, 2026 |
Est. primary completion date | February 15, 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility | Inclusion Criteria: - ages of 18-65 years old - not pregnant - no comorbid conditions - normal BMI (18.5 - 24.9 kg/m2) - Weight =120 lbs self-reported weight Exclusion Criteria: - N/A |
Country | Name | City | State |
---|---|---|---|
United States | University of Minnesota | Minneapolis | Minnesota |
Lead Sponsor | Collaborator |
---|---|
University of Minnesota |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Inflammatory markers quantification | employ a the MILLIPLEX ® Human Cytokine/Chemokine Multiplex Assay Panel to quantify 50 specific inflammatory markers in the serum samples. | 8 months | |
Primary | quantitative metabolomics on serum samples | leverage the University of Minnesota Center for Metabolomics and Proteomics to conduct analysis of serum samples utilizing the Biocrates MxP Quant 500, which provides detailed quantification of over 500 individual metabolites. | 8 months |
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