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Clinical Trial Summary

This double-blind, randomized, placebo-controlled study will assess the safety and pharmacokinetics of ZB002 in healthy participants and in participants with rheumatoid arthritis (RA). The study consists of 2 parts. Part A: Single Ascending Dose (SAD), which will include only healthy volunteers. Part B: Multiple Ascending Dose (MAD), will commence after completion of the SAD study and will include RA participants.


Clinical Trial Description

Part A (SAD): Up to approximately 48 healthy volunteers across 6 cohorts randomized to receive ZB002 or placebo as a single dose. Part B (MAD): Up to approximately 24 participants with RA across 3 cohorts randomized to receive ZB002 or placebo as multiple doses. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05638854
Study type Interventional
Source Zenas BioPharma (USA), LLC
Contact
Status Active, not recruiting
Phase Phase 1
Start date December 8, 2022
Completion date July 2025

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