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Clinical Trial Summary

This is a randomized, double-blind, placebo-controlled, 2-part study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple ascending doses of SR1375 in healthy volunteers


Clinical Trial Description

This study is a phase 1,randomized, double-blind, placebo-controlled, 2-part study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple ascending doses of SR1375 in healthy volunteers. The study is divided into two parts, Part A (single ascending dose [SAD]) and Part B (multiple ascending dose [MAD]). In Part A, the scheduled dose cohorts include 1, 3, 10, 30, 100, and 200 mg; in Part B, the planned dose range will be 5, 15, and 50 mg. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05026008
Study type Interventional
Source Shanghai SIMR Biotechnology Co., Ltd.
Contact Pan Wang
Phone +86 13795373965
Email [email protected]
Status Not yet recruiting
Phase Phase 1
Start date September 2021
Completion date March 2022

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