Motor Language Learning — MOTOLANGUAGE  

Healthy Volunteers Clinical Trial

Official title: A Motor Tool for Language Learning

Status Recruiting

Clinical Trial Summary

This project pursues the validation of an innovative strategy to boost language learning, based on the benefits derived from sensorimotor training.

The common belief of a rigid brain structure in adult life had to be reconsidered during the last decade. After training, local increase in cerebral cortex volume and thickness, the part of the brain containing neuronal cells and synapses, has been documented. Research has established that brain structures active during training expand while learning and return to baseline afterwards. The transient structural increase is thought to reflect "work in progress" within areas involved in learning, meant to integrate new skills in existing neural circuitries, via strengthening and/or selection of local neuronal connections. My main hypothesis is that other functions, as long as they rely on the activity of the same brain territories, can take advantage of this "work in progress". To use an allegory, imagine the restauration of a building (brain area). It can start after the request of improvements from some of the residents (trained function) and then become the occasion for other tenants (other functions) to see realized also their own wish for improvements. In the end everybody will benefit from the restauration, provided that they all live in the same building and everybody has posed their requests during the "work in progress". Out of the allegory, living in the same building means neural overlap of functions in the brain. The case of motor and linguistic systems represents, from this perspective, a unique opportunity. State-of-the-art research 1) proved the existence, and described the temporal evolution of brain plastic changes during sensorimotor learning, and 2) documented neural overlap and functional interactions of motor and linguistic systems. This posits solid bases for a crucial step forward, gravid of important consequences and applications. This project aims to take this step forward by directly testing the innovative hypothesis that brain changes induced by sensorimotor learning induce benefits for linguistic functions relying on the same brain territories.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Healthy Volunteers

• NCT number: NCT03223090
• Study type: Interventional
• Source: Hospices Civils de Lyon
• Contact: Claudio BROZZOLI
• Phone: 0472913410
• Email: Claudio.brozzoli@inserm.fr
• Status: Recruiting
• Phase: N/A
• Start date: January 19, 2018
• Completion date: March 19, 2026