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NCT02951494 Clinical Trial

Impact of Lower Body Weight Support Treadmill on Cardiopulmonary Exercise Capacity and Trainability

Healthy Volunteers Clinical Trial

Official title:
Einfluss Der Körpergewichtsunterstützung Auf Einem AlterG®-Antigravitationslaufband Auf Die Kardiopulmonale Leistungsfähigkeit Und Trainierbarkeit

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02951494
Other study ID # AlterG-Training-I Studie
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date January 2017
Est. completion date December 31, 2021

Study information
Verified date September 2021
Source University Medicine Greifswald
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The AlterG®-anti-gravity treadmill provides lower body weight support which enables individuals to exercise without feeling their full body weight. How this body weight support influences cardiovascular, respiratory, vascular and metabolic parameters is currently unclear. Further, whether body weight support influences the trainability in response to moderate continuous exercise is unknown. This investigation has two main goals. First, we explore the direct influence of lower body weight support on cardiometabolic parameters during maximal exercise testing. Second, we aim to compare changes in cardiorespiratory fitness in response to a structured exercise protocol using moderate intensity with and without lower body weight support.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date December 31, 2021
Est. primary completion date December 31, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 45 Years
Eligibility Inclusion Criteria: - maximal oxygen consumption below age-sex specific standard Exclusion Criteria: - acute infection within the last four weeks - anemia (males: Hb < 8.1 mmol/L; females Hb < 7.4 mmol/L) - previous reports of myo-, endo, or pericarditis - previous stroke or acute myocardial infarction - heart failure (NYHA > 1) - aortic valve stenosis - congenital heart disease - cardiomyopathy - severe left ventricular hypertrophy - cardiac arrythmias - hypertension - diabetes - BMI > 35 - cancer - pregnancy - aneurysm of aorta or cerebral arteries

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• AlterG Anti-gravity treadmill
Participants in this group will complete a 12 week aerobic exercise training protocol with 40% lower body weight support on an AlterG Anti-gravity treadmill

Locations
Country Name City State
Germany Cardiovascular examination center of the University Medicine Greifswald Greifswald

Sponsors (1)
Lead Sponsor Collaborator
University Medicine Greifswald

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Maximal oxygen consumption VO2peak [ml/min] 12 weeks
Secondary Oxygen consumption at anaerobic threshold VO2@AT 12 weeks
Secondary Pulse wave velocity 12 weeks
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