Healthy Volunteers Clinical Trial
Official title:
A Phase 1, Open-label, Randomized, Single-dose, 3-period Cross-over, Relative Bioavailability Study to Assess Two Solid Formulations Compared to an Oral Solution of AZD3293 in Healthy Male and Non-Fertile Female Subjects
This is an open-label, randomized, 3-period crossover, single dose study. Three (3) single
doses of AZD3293 (2 different tablet formulations, and an oral solution) will be
administered with a washout period of at least 1 week between the doses to investigate the
relative bioavailability of AZD3293 after administration via 2 tablet formulations compared
with oral solution and to evaluate basic systemic pharmacokinetic parameters of the tablet
formulations compared to the oral solution of AZD3293.
The safety and tolerability of AZD3293 in healthy subjects will also be assessed in the
study. AZD3293 is being developed for the treatment of Alzheimer's disease
n/a
Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science
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