Healthy Volunteer Clinical Trial
Official title:
Collection of Saliva and/ or Peripheral Blood From Healthy Volunteers for Research
Verified date | July 2022 |
Source | National Institutes of Health Clinical Center (CC) |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Background: - Researchers often collect samples from healthy volunteers to further their research. These samples can help better understand serious side effects and complications of transplant treatments in patients. This study will collect saliva samples from healthy volunteers. Objectives: - To collect saliva and blood samples from healthy volunteers for research studies. Eligibility: - Healthy men ages 30-70 years for Phase I of the study. Design: - Participants will be screened with a medical history questionnaire. They will also have a brief oral exam to check for any mouth infection. - Participants will provide a saliva sample. The collection process will take about 5 minutes. - No treatment will be given as part of this study.
Status | Completed |
Enrollment | 29 |
Est. completion date | February 12, 2015 |
Est. primary completion date | July 10, 2014 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 99 Years |
Eligibility | - INCLUSION CRITERIA: - Healthy individuals (including employees) and other healthy volunteers from all racial/ethnic groups - Age 18 years and older, with possible restriction for age-matching to patient samples. - Ability of subject to understand and provide written informed consent - Subjects must participate fully and be willing to comply with the procedures of the protocol - Phase I of the study will be restricted to males, age 30-70 years. EXCLUSION CRITERIA: - Active systemic illnesses, immunodeficiency, history of opportunistic infection, autoimmune disease, immunosuppressive medications - Prior organ, bone marrow or peripheral blood stem cell transplant - Acute dental infection |
Country | Name | City | State |
---|---|---|---|
United States | National Institutes of Health Clinical Center, 9000 Rockville Pike | Bethesda | Maryland |
Lead Sponsor | Collaborator |
---|---|
National Cancer Institute (NCI) |
United States,
Bassim CW, Ambatipudi KS, Mays JW, Edwards DA, Swatkoski S, Fassil H, Baird K, Gucek M, Melvin JE, Pavletic SZ. Quantitative salivary proteomic differences in oral chronic graft-versus-host disease. J Clin Immunol. 2012 Dec;32(6):1390-9. doi: 10.1007/s10875-012-9738-4. Epub 2012 Jul 18. — View Citation
Mays JW, Fassil H, Edwards DA, Pavletic SZ, Bassim CW. Oral chronic graft-versus-host disease: current pathogenesis, therapy, and research. Oral Dis. 2013 May;19(4):327-46. doi: 10.1111/odi.12028. Epub 2012 Oct 28. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Collect saliva and peripheral blood | Sample analysis for research. | End of specimen collection |
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