Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

Healthy Volunteers Clinical Trial

Official title:

Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01752868
• Other study ID #: BJH 6936-33
• Status: Completed
• Phase: N/A
• First received: December 14, 2012
• Last updated: December 14, 2012
• Start date: May 2011
• Est. completion date: August 2012

Study information

• Verified date: December 2012
• Source: Washington University School of Medicine
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine if a combination of 10 nutritional supplements provide health benefits that are consistent with protection against age-related disease. All supplements have been shown in previous studies to have health benefits when administered alone. The hypothesis is that 6 months of taking 10 nutritional supplements each day will provide beneficial changes in healthy related measures.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 56
• Est. completion date: August 2012
• Est. primary completion date: August 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 40 Years to 60 Years

Eligibility

Inclusion Criteria:

• age 40-60 yr

• body mass index of 21 - 30 kg/m2

• sedentary to moderately active

• eating a typical US diet

Exclusion Criteria:

• history of any chronic disease other than mild osteoarthritis

• use of medications other than occasional use of non-steroidal anti-inflammatory drugs, antihistamines, antacids or laxatives

• use of nutritional supplements

• smoking

• alcohol intake greater than two drinks per day for women and three drinks per day for men

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Healthy Volunteers

Intervention

Dietary Supplement:
• Supplement
Participants in this group will take the following nutritional supplements on a daily basis: curcumin, fish oil, resveratrol, sesamin, Acetyl-L-carnitine, lipoic acid, green and black teas, quercetin, pomegranate, cinnamon bark.

Locations

Country	Name	City	State
United States	Washington University Medical Center	St. Louis	Missouri

Sponsors (2)

Lead Sponsor	Collaborator
Washington University School of Medicine	Barnes-Jewish Hospital

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Carotid-femoral pulse wave velocity		Baseline and 6 months	No