Healthy Volunteers Clinical Trial
Official title:
Accuracy of Oximeters With Hypoxia and Methemoglobin or Carboxyhemoglobin
Accuracy of the oximeter.
The conventional pulse oximeter has been a standard in clinical care for non-invasive
hemodynamic monitoring, which only measures the arterial blood oxygenation. There are many
clinical situations where tissue hypoxia may exist despite normal values obtained by
conventional pulse oximeter. This can be cause by inadequate monitoring of oxygen demand
(i.e. venous oxygen saturation) of the tissues.
The existing method for venous blood oxygenation monitored is either through an invasive
fiber optic catheter, or intermittently by blood sampling and CO-oximetry. However,
catheterization can be costly and can include inherent risks. Therefore, due to the inherent
risks of catheterization, venous oximetry is limited only to those critically ill patients.
The clinical application of venous oximetry is numerous, including severe sepsis and septic
shock, severe trauma and hemorrhagic shock, and heart failure and cardiac arrest.
More complete information on patient hemodynamics can be provided by non-invasively
monitoring of venous blood oxygenation.
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