Healthy Volunteers Clinical Trial
Official title:
A Placebo-Controlled, Single Dose, Dose Escalation (Part A) and a Placebo- and Positive-Controlled Study of the Effect on the Electrocardiographic QT Interval of a Single Dose (Part B) of LY3009104 in Healthy Subjects
This will be a 2-part, randomized, subject- and investigator-blind study in healthy males
and females.
Part A of this study is to determine a safe and tolerable single oral dose of LY3009104 that
yields drug exposures slightly exceeding typical exposures anticipated from repeated
administration of an efficacious dose to patients. The concentration of the drug in the
blood stream will be measured and information about any side effects that may occur will
also be collected.
Part B of this study is to evaluate the effect of LY3009104 on the electrical activity of
the heart as measured by electrocardiogram (ECG) in relation to placebo following a single
oral dose.
n/a
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science
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